Nodular lymphoma associated with macroglobulinaemia

A case is described of multiple adenopathy with hepatosplenomegaly, lymphocyte infiltration of the bone marrow, IgM paraprotein in the plasma and type Kappa Bence Jones proteinuria, with lymph gland histology corresponding to a nodular lymphoma. During the evolution there was a reduction of the tumor masses and of the protein anomalies, which were still present a year later. The demarcation line existing between true macroglobulinemia and immunoglobulin secreting lymphoma is discussed.