No increase in micronuclei frequency in cultured blood lymphocytes from a group of filling station attendants

M. Pitarque, E. Carbonell, N. Lapeña, M. Marsá, M. Torres, A. Creus, N. Xamena, R. Marcos

Sortida de recercaRecercarevisió per companys

40 Cites (Scopus)

Resum

Service station attendants are workers that are definitely exposed to petroleum derivatives. Taking into account that this exposure has been considered to possess genotoxic risk, here we present data on the biomonitoring of a group of 50 service station workers and 43 controls. Micronuclei (MN) from peripheral blood lymphocytes has been considered as the genetic endpoint to be studied and, in addition, data on the concentration of aromatic hydrocarbons at the workplace, urinary metabolites and differential white blood cell count have also been analysed. The results obtained indicate no significant differences between petrol station attendants and controls, when the effects of petrol exposure were investigated by differential white blood cell count and analysis of MN frequencies in phytohaemagglutinin-stimulated lymphocytes. Regarding the urinary metabolites, a significant increase in the phenol level was found in the exposed workers.
Idioma originalEnglish
Pàgines (de-a)161-167
RevistaMutation Research - Genetic Toxicology
Volum367
Número d'incidència3
DOIs
Estat de la publicacióPublicada - 1 de gen. 1996

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