New approaches but the same flaws in the search for prognostic signatures

Ramon Salazar; Josep Tabernero

doi:10.1158/1078-0432.CCR-14-0219

New approaches but the same flaws in the search for prognostic signatures

Ramon Salazar, Josep Tabernero

Departament de Medicina

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Resum

A six-gene prognostic colorectal cancer hypoxia score was generated from expression data from in vitro experiments and microarray datasets and was validated in two distinct patient cohorts. The approach followed by the authors is original and biologically sound but could be limited by potential biases and other methodologic limitations. © 2014 AACR.

Idioma original	English
Pàgines (de-a)	2019-2022
Revista	Clinical Cancer Research
Volum	20
Número	8
DOIs	https://doi.org/10.1158/1078-0432.CCR-14-0219
Estat de la publicació	Publicada - 15 d’abr. 2014

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10.1158/1078-0432.CCR-14-0219

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title = "New approaches but the same flaws in the search for prognostic signatures",

abstract = "A six-gene prognostic colorectal cancer hypoxia score was generated from expression data from in vitro experiments and microarray datasets and was validated in two distinct patient cohorts. The approach followed by the authors is original and biologically sound but could be limited by potential biases and other methodologic limitations. {\textcopyright} 2014 AACR.",

author = "Ramon Salazar and Josep Tabernero",

year = "2014",

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doi = "10.1158/1078-0432.CCR-14-0219",

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T1 - New approaches but the same flaws in the search for prognostic signatures

AU - Salazar, Ramon

AU - Tabernero, Josep

PY - 2014/4/15

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N2 - A six-gene prognostic colorectal cancer hypoxia score was generated from expression data from in vitro experiments and microarray datasets and was validated in two distinct patient cohorts. The approach followed by the authors is original and biologically sound but could be limited by potential biases and other methodologic limitations. © 2014 AACR.

AB - A six-gene prognostic colorectal cancer hypoxia score was generated from expression data from in vitro experiments and microarray datasets and was validated in two distinct patient cohorts. The approach followed by the authors is original and biologically sound but could be limited by potential biases and other methodologic limitations. © 2014 AACR.

U2 - 10.1158/1078-0432.CCR-14-0219

DO - 10.1158/1078-0432.CCR-14-0219

M3 - Article

SN - 1078-0432

VL - 20

SP - 2019

EP - 2022

JO - Clinical Cancer Research

JF - Clinical Cancer Research

IS - 8

ER -

New approaches but the same flaws in the search for prognostic signatures

Resum

SDG de les Nacions Unides

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