Neuritis óptica, síndromes del tronco y mielitis: Conversión temprana a esclerosis múltiple

M Tintoré; A Rovira; D Hernández; J Río; ME Marzo; X Montalban

Neuritis óptica, síndromes del tronco y mielitis: Conversión temprana a esclerosis múltiple

M Tintoré, A Rovira, D Hernández, J Río, ME Marzo, X Montalban

Departament de Medicina

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

6 Cites (Scopus)

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BACKGROUND: To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD: 36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including clinical data, immunological determinations, oligoclonal bands, visual, somestesic and brainstem evoked potentials and a magnetic resonance imaging (MRI) study. RESULTS: MRI showed the presence of signal abnormalities in 70% of the patients. The conversion rate (CR) was 18.5%. In patients with a normal MRI, CR was 4% compared to 26% in patients with an abnormal MRI (p = 0.05). CONCLUSIONS: The early conversion rate to MS is significantly increased when MRI is abnormal.

Títol traduït de la contribució	Optic neuritis, brain stem syndromes and myelitis: rapid conversion to multiple sclerosis]
Idioma original	Espanyol
Pàgines (de-a)	693-694
Nombre de pàgines	2
Revista	Medicina Clínica (Barcelona)
Volum	112
Número	18
Estat de la publicació	Publicada - 22 de maig 1999

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@article{9e2e7209b18c4edda6d65715252746f1,

title = "Neuritis {\'o}ptica, s{\'i}ndromes del tronco y mielitis: Conversi{\'o}n temprana a esclerosis m{\'u}ltiple",

abstract = "BACKGROUND: To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD: 36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including clinical data, immunological determinations, oligoclonal bands, visual, somestesic and brainstem evoked potentials and a magnetic resonance imaging (MRI) study. RESULTS: MRI showed the presence of signal abnormalities in 70\% of the patients. The conversion rate (CR) was 18.5\%. In patients with a normal MRI, CR was 4\% compared to 26\% in patients with an abnormal MRI (p = 0.05). CONCLUSIONS: The early conversion rate to MS is significantly increased when MRI is abnormal.",

author = "M Tintor{\'e} and A Rovira and D Hern{\'a}ndez and J R{\'i}o and ME Marzo and X Montalban",

year = "1999",

month = may,

day = "22",

language = "Espa{\~n}ol",

volume = "112",

pages = "693--694",

journal = "Medicina Cl{\'i}nica (Barcelona)",

issn = "0025-7753",

publisher = "Elsevier",

number = "18",

}

TY - JOUR

T1 - Neuritis óptica, síndromes del tronco y mielitis

T2 - Conversión temprana a esclerosis múltiple

AU - Tintoré, M

AU - Rovira, A

AU - Hernández, D

AU - Río, J

AU - Marzo, ME

AU - Montalban, X

PY - 1999/5/22

Y1 - 1999/5/22

N2 - BACKGROUND: To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD: 36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including clinical data, immunological determinations, oligoclonal bands, visual, somestesic and brainstem evoked potentials and a magnetic resonance imaging (MRI) study. RESULTS: MRI showed the presence of signal abnormalities in 70% of the patients. The conversion rate (CR) was 18.5%. In patients with a normal MRI, CR was 4% compared to 26% in patients with an abnormal MRI (p = 0.05). CONCLUSIONS: The early conversion rate to MS is significantly increased when MRI is abnormal.

AB - BACKGROUND: To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD: 36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including clinical data, immunological determinations, oligoclonal bands, visual, somestesic and brainstem evoked potentials and a magnetic resonance imaging (MRI) study. RESULTS: MRI showed the presence of signal abnormalities in 70% of the patients. The conversion rate (CR) was 18.5%. In patients with a normal MRI, CR was 4% compared to 26% in patients with an abnormal MRI (p = 0.05). CONCLUSIONS: The early conversion rate to MS is significantly increased when MRI is abnormal.

UR - http://europepmc.org/abstract/med/10374200

UR - https://www.scopus.com/pages/publications/0033594588

M3 - Artículo

C2 - 10374200

SN - 0025-7753

VL - 112

SP - 693

EP - 694

JO - Medicina Clínica (Barcelona)

JF - Medicina Clínica (Barcelona)

IS - 18

ER -

Neuritis óptica, síndromes del tronco y mielitis: Conversión temprana a esclerosis múltiple

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