TY - JOUR
T1 - Multicenter evaluation of Neo-Sensitabs, a standardized diffusion method for yeast susceptibility testing
AU - Carrillo-Muñoz, Alfonso Javier
AU - Abarca, Lourdes
AU - Quindós, Guillermo
AU - Arévalo, Pilar
AU - Bornay, Fernando
AU - Cabañes, Francisco Javier
AU - Casals, José B.
AU - Estivill, Dolors
AU - Gonzalez-Lama, Zoilo
AU - Iglesias, Isabel
AU - Hernández-Molina, Juan Manuel
AU - Linares, Ma José
AU - Martín-Mazuelos, Estrella
AU - Payá, Majesús
AU - Pereiro, Manuel
AU - Millán, Rosario San
AU - Rubio, Ma Carmen
PY - 1999/6/1
Y1 - 1999/6/1
N2 - The agar diffusion method Neo-Sensitabs for sensitivity testing, was evaluated with 33 reference strains by fourteen laboratories. Tablets with 5- fluorocytosine, amphotericin B, nystatin, fluconazole, itraconazole, ketoconazole and tioconazole were used on Shadomy modified medium. These tests classify each strain as susceptible, intermediate or resistant to all tested antifungals by measuring the inhibition zone diameters. Intra and interlaboratory reproducibility was studied. Neo-Sensitabs sensitivity for fungi was easy to perform and reliable method with a reproducibility of 97.1% and superior to other commercialized methods, being specially interesting for antifungal susceptibility in vitro testing of triazole derivatives fluconazole and itraconazole.
AB - The agar diffusion method Neo-Sensitabs for sensitivity testing, was evaluated with 33 reference strains by fourteen laboratories. Tablets with 5- fluorocytosine, amphotericin B, nystatin, fluconazole, itraconazole, ketoconazole and tioconazole were used on Shadomy modified medium. These tests classify each strain as susceptible, intermediate or resistant to all tested antifungals by measuring the inhibition zone diameters. Intra and interlaboratory reproducibility was studied. Neo-Sensitabs sensitivity for fungi was easy to perform and reliable method with a reproducibility of 97.1% and superior to other commercialized methods, being specially interesting for antifungal susceptibility in vitro testing of triazole derivatives fluconazole and itraconazole.
KW - Antifungal susceptibility
KW - Collaborative study
KW - Neo-Sensitabs
M3 - Article
SN - 1130-1406
VL - 16
SP - 92
EP - 96
JO - Revista Iberoamericana de Micologia
JF - Revista Iberoamericana de Micologia
IS - 2
ER -