TY - JOUR
T1 - Mouse models of diabetic retinopathy
AU - Ramos, D
AU - Carretero, A
AU - Navarro, M
AU - Mendes-Jorge, L
AU - Rodríguez-Baeza, A
AU - Nacher, V
AU - Ruberte, J.
N1 - Funding Information:
We thank V. Melgarejo, L. Noya and A. Vazquez for technical assistance. This work was supported by grants PS09/01152 and PI12/00605 from the Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación, Spain and PTDC/SAU-ORG/110856/2009 from the Fundação para a Ciência e a Tecnologia do Ministério da Ciência, Tecnologia e Ensino Superior, Portugal .
Publisher Copyright:
© 2014 Elsevier Ltd
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2013/2/4
Y1 - 2013/2/4
N2 - Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. Mouse models have been valuable tools in further understanding the pathophysiology of diabetic retinopathy and discovering and assessing new potential therapeutic agents. However, although numerous diabetic mouse models have been developed, none of these models replicates all the key features of human diabetic retinopathy. In this review, we summarize and update the list of mouse diabetic and diabetic-like models that have been generated.
AB - Despite many years of clinical and laboratory investigation, diabetic retinopathy remains the leading cause of vision impairment among working-aged people. Mouse models have been valuable tools in further understanding the pathophysiology of diabetic retinopathy and discovering and assessing new potential therapeutic agents. However, although numerous diabetic mouse models have been developed, none of these models replicates all the key features of human diabetic retinopathy. In this review, we summarize and update the list of mouse diabetic and diabetic-like models that have been generated.
UR - http://www.scopus.com/inward/record.url?scp=84901385783&partnerID=8YFLogxK
U2 - 10.1016/j.ddmod.2014.02.002
DO - 10.1016/j.ddmod.2014.02.002
M3 - Review article
SN - 1740-6757
VL - 10
SP - e195-e206
JO - Drug Discovery Today: Disease Models
JF - Drug Discovery Today: Disease Models
IS - 4
ER -
