TY - JOUR
T1 - Molecular tweezers for enantiodiscrimination in NMR: Di-(R,R)-1-[10-(1- hydroxy-2,2,2-trifluoroethyl)-9-anthryl]-2,2, 2-trifluoroethyl benzenedicarboxylates
AU - Gil, Sergio
AU - Palomino-SchäTzlein, Martina
AU - Burusco, Kepa Koldo
AU - Jaime, Carlos
AU - Virgili, Albert
PY - 2010/6/1
Y1 - 2010/6/1
N2 - A series of new chiral molecular tweezers, di-(R,R)-1-[10-(1-hydroxy-2,2,2- trifluoroethyl)-9-anthryl]-2,2,2-trifluoroethyl phthalate (2), isophthalate (3) and terephthalate (4), were synthesized and their structure studied by NMR and molecular mechanics. Their effectiveness as chiral solvating agents for the determination of the enantiomeric purity of chiral compounds using NMR was demonstrated. © 2009 Wiley-Liss, Inc.
AB - A series of new chiral molecular tweezers, di-(R,R)-1-[10-(1-hydroxy-2,2,2- trifluoroethyl)-9-anthryl]-2,2,2-trifluoroethyl phthalate (2), isophthalate (3) and terephthalate (4), were synthesized and their structure studied by NMR and molecular mechanics. Their effectiveness as chiral solvating agents for the determination of the enantiomeric purity of chiral compounds using NMR was demonstrated. © 2009 Wiley-Liss, Inc.
KW - Chiral solvating agents
KW - Enantiodiscrimination
KW - Enantiomeric excess
KW - Molecular tweezers
KW - NMR
UR - https://www.scopus.com/pages/publications/77951554643
U2 - 10.1002/chir.20786
DO - 10.1002/chir.20786
M3 - Article
SN - 0899-0042
VL - 22
SP - 548
EP - 556
JO - Chirality
JF - Chirality
IS - 6
ER -