TY - JOUR
T1 - Management of chronic spontaneous urticaria exacerbated by antihistamines: When treatment can act as a causal agent itself
AU - Deza, Gustavo
AU - García-Colmenero, Lidia
AU - Curto-Barredo, Laia
AU - Pujol, Ramon M.
AU - Giménez-Arnau, Ana M.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - © 2016 The Authors. Although H1-antihistamines currently constitute the largest class of medications used in the treatment of allergic disorders, some cases of hypersensitivity reactions due to various antihistamine preparations, such as fixed drug eruptions, contact dermatitis, maculo-papular rash, and urticarial reactions, have been reported (1). We report here 2 cases of patients with chronic spontaneous urticaria (CSU) in which antihistamines were an exacerbating factor of the disease and alternative treatment was required. The underlying mechanism in these cases is not entirely clear, but a type-I (immediate) hypersensitivity reaction should be considered.
AB - © 2016 The Authors. Although H1-antihistamines currently constitute the largest class of medications used in the treatment of allergic disorders, some cases of hypersensitivity reactions due to various antihistamine preparations, such as fixed drug eruptions, contact dermatitis, maculo-papular rash, and urticarial reactions, have been reported (1). We report here 2 cases of patients with chronic spontaneous urticaria (CSU) in which antihistamines were an exacerbating factor of the disease and alternative treatment was required. The underlying mechanism in these cases is not entirely clear, but a type-I (immediate) hypersensitivity reaction should be considered.
U2 - 10.2340/00015555-2403
DO - 10.2340/00015555-2403
M3 - Article
SN - 0001-5555
VL - 96
SP - 838
EP - 839
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
IS - 6
ER -