TY - JOUR
T1 - Magnetic carbon gate electrodes for the development of electrolyte-gated organic field effect transistor bio-sensing platforms
AU - Tamayo, A.
AU - Muñoz, J.
AU - Martínez-Domingo, C.
AU - Mas-Torrent, M.
N1 - Publisher Copyright:
© 2023 The Royal Society of Chemistry
PY - 2023
Y1 - 2023
N2 - Electrolyte-gated organic field-effect transistors (EGOFETs) are promising devices for the development of bio-sensors. Typically, a gold gate electrode is functionalised with a self-assembled monolayer bearing the bio-receptor. Here, we propose a new route to fabricate EGOFET sensors using magnetic carbon-paste gate electrodes. In this way, magnetic nanoparticles properly modified with a bio-receptor are incubated with the analyte and, subsequently, collected on the gate electrode surface. Remarkably, these electrodes can be polished and re-used after each measurement. The feasibility of this route is here demonstrated for the biotin-avidin/streptavidin supramolecular complexes. High sensitivities and low limits of detection of the order of fM are achieved. Hence, this work demonstrates a novel and versatile strategy to exploit EGOFETs as sensing platforms.
AB - Electrolyte-gated organic field-effect transistors (EGOFETs) are promising devices for the development of bio-sensors. Typically, a gold gate electrode is functionalised with a self-assembled monolayer bearing the bio-receptor. Here, we propose a new route to fabricate EGOFET sensors using magnetic carbon-paste gate electrodes. In this way, magnetic nanoparticles properly modified with a bio-receptor are incubated with the analyte and, subsequently, collected on the gate electrode surface. Remarkably, these electrodes can be polished and re-used after each measurement. The feasibility of this route is here demonstrated for the biotin-avidin/streptavidin supramolecular complexes. High sensitivities and low limits of detection of the order of fM are achieved. Hence, this work demonstrates a novel and versatile strategy to exploit EGOFETs as sensing platforms.
KW - Avidin
KW - Biosensors
KW - Paste electrodes
KW - Polymer
KW - Surface
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-85169546163&partnerID=MN8TOARS
UR - https://www.mendeley.com/catalogue/17e1a1e5-6683-34a9-91f5-0c5575d68429/
U2 - 10.1039/d3tc01655b
DO - 10.1039/d3tc01655b
M3 - Article
SN - 2050-7526
VL - 11
SP - 11912
EP - 11919
JO - Journal of Materials Chemistry C
JF - Journal of Materials Chemistry C
IS - 35
ER -