TY - JOUR
T1 - Long term follow-up of non-symptomatic HBsAg carriers
AU - González, A.
AU - Vargas, V.
AU - Hernández-Sánchez, J. M.
AU - Cortina, M.
AU - Pelegrí, D.
AU - López-Talavera, J. C.
AU - Genescá, J.
AU - Jardí, R.
AU - Esteban, R.
AU - Guardia, J.
PY - 1991/1/1
Y1 - 1991/1/1
N2 - 232 asymptomatic HBsAg carriers were controlled between May/1986 and May/1990. The were detected in our blood bank between 1974 and 1976 or during pregnancy or delivery period after 1981. 23 of 232 (10%) became negative during the follow-up, this happening more frequently in carriers after 5 years of follow-up. Only 2 of 209 carriers with HBsAg were HBeAg positive and 1 of these was also DNA-VHB positive. None of the HBeAg negative carriers showed DNA-VHB; only 5 had increased transaminases. 7 were anti-VHC positive, these individuals experiencing more frequent increases in transaminases. The results of this study suggests that the determination of transaminases, viral activity markers, anti-HD, anti-VHC in HBsAg carriers are enough to identify those with hepatic disease.
AB - 232 asymptomatic HBsAg carriers were controlled between May/1986 and May/1990. The were detected in our blood bank between 1974 and 1976 or during pregnancy or delivery period after 1981. 23 of 232 (10%) became negative during the follow-up, this happening more frequently in carriers after 5 years of follow-up. Only 2 of 209 carriers with HBsAg were HBeAg positive and 1 of these was also DNA-VHB positive. None of the HBeAg negative carriers showed DNA-VHB; only 5 had increased transaminases. 7 were anti-VHC positive, these individuals experiencing more frequent increases in transaminases. The results of this study suggests that the determination of transaminases, viral activity markers, anti-HD, anti-VHC in HBsAg carriers are enough to identify those with hepatic disease.
M3 - Article
SN - 0212-7199
VL - 8
SP - 269
EP - 272
JO - Anales de medicina interna (Madrid, Spain : 1984)
JF - Anales de medicina interna (Madrid, Spain : 1984)
IS - 6
ER -