Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data

J Sastre-Garriga; GT Ingle; M Rovaris; N Tellez; B Jasperse; DR Altmann; B Benedetti; VL Stevenson; M Cercignani; SM Leary; F Barkhof; B Brochet; V Dousset; M Filippi; X Montalban; NF Kalkers; CH Polman; A Rovira; DH Miller; AJ Thompson

doi:10.1212/01.wnl.0000173061.12776.1f

Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data

J Sastre-Garriga, GT Ingle, M Rovaris, N Tellez, B Jasperse, DR Altmann, B Benedetti, VL Stevenson, M Cercignani, SM Leary, F Barkhof, B Brochet, V Dousset, M Filippi, X Montalban, NF Kalkers, CH Polman, A Rovira, DH Miller, AJ Thompson

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Resum

The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years ( clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.

Idioma original	Anglès
Pàgines (de-a)	633-635
Nombre de pàgines	3
Revista	Neurology
Volum	65
Número	4
DOIs	https://doi.org/10.1212/01.wnl.0000173061.12776.1f
Estat de la publicació	Publicada - 23 d’ag. 2005

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10.1212/01.wnl.0000173061.12776.1f

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Genetics of anxiety in genetically heterogeneous N/Nih and inbred Roman rats: diferential gene expression in target brain areas
Fernandez Teruel, A. (PI), Anegón, I. (Investigador/a), Blázquez Romero, G. (Investigador/a), Cañete Ramírez, A. (Investigador/a), Flint, J. (Investigador/a), Johannesson, M. (Investigador/a), López Aumatell, R. (Investigador/a), Martínez Membrives, E. (Investigador/a), Tesson, L. (Investigador/a), Tobeña Pallares, A. (Investigador/a) & Vicens Costa, E. (Investigador/a)
Fundació La Marató de TV3
1/03/10 → 15/03/14
Projecte: Projectes i Ajuts a la Recerca

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Sastre-Garriga, J., Ingle, GT., Rovaris, M., Tellez, N., Jasperse, B., Altmann, DR., Benedetti, B., Stevenson, VL., Cercignani, M., Leary, SM., Barkhof, F., Brochet, B., Dousset, V., Filippi, M., Montalban, X., Kalkers, NF., Polman, CH., Rovira, A., Miller, DH., & Thompson, AJ. (2005). Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data. Neurology, 65(4), 633-635. https://doi.org/10.1212/01.wnl.0000173061.12776.1f

@article{539320cefa3640c5b72211958d3ba712,

title = "Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data",

abstract = "The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years ( clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.",

keywords = "Multiple-sclerosis, Metrics",

author = "J Sastre-Garriga and GT Ingle and M Rovaris and N Tellez and B Jasperse and DR Altmann and B Benedetti and VL Stevenson and M Cercignani and SM Leary and F Barkhof and B Brochet and V Dousset and M Filippi and X Montalban and NF Kalkers and CH Polman and A Rovira and DH Miller and AJ Thompson",

year = "2005",

month = aug,

day = "23",

doi = "10.1212/01.wnl.0000173061.12776.1f",

language = "English",

volume = "65",

pages = "633--635",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

number = "4",

}

Sastre-Garriga, J, Ingle, GT, Rovaris, M, Tellez, N, Jasperse, B, Altmann, DR, Benedetti, B, Stevenson, VL, Cercignani, M, Leary, SM, Barkhof, F, Brochet, B, Dousset, V, Filippi, M, Montalban, X, Kalkers, NF, Polman, CH, Rovira, A, Miller, DH & Thompson, AJ 2005, 'Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data', Neurology, vol. 65, núm. 4, pàg. 633-635. https://doi.org/10.1212/01.wnl.0000173061.12776.1f

TY - JOUR

T1 - Long-term clinical outcome of primary progressive MS

T2 - Predictive value of clinical and MRI data

AU - Sastre-Garriga, J

AU - Ingle, GT

AU - Rovaris, M

AU - Tellez, N

AU - Jasperse, B

AU - Altmann, DR

AU - Benedetti, B

AU - Stevenson, VL

AU - Cercignani, M

AU - Leary, SM

AU - Barkhof, F

AU - Brochet, B

AU - Dousset, V

AU - Filippi, M

AU - Montalban, X

AU - Kalkers, NF

AU - Polman, CH

AU - Rovira, A

AU - Miller, DH

AU - Thompson, AJ

PY - 2005/8/23

Y1 - 2005/8/23

N2 - The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years ( clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.

AB - The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years ( clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.

KW - Multiple-sclerosis

KW - Metrics

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U2 - 10.1212/01.wnl.0000173061.12776.1f

DO - 10.1212/01.wnl.0000173061.12776.1f

M3 - Article

C2 - 16116134

SN - 0028-3878

VL - 65

SP - 633

EP - 635

JO - Neurology

JF - Neurology

IS - 4

ER -

Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data

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Genetics of anxiety in genetically heterogeneous N/Nih and inbred Roman rats: diferential gene expression in target brain areas

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