Kawasaki disease. Update and review of the casuistics in our center in the last 10 years

Kawasaki disease (KD) is a systemic vasculitis, acute, self-limited, with potentially dangerous complications, which mainly affects infants and young children (age<5 years), but also seen in adolescents and adults. The EK is the leading cause of acquired heart disease in children in developed countries and their impact on our environment is 15.1/100,000 children < 5 years/year, similar to the U.S. and European countries. Without treatment, up to 25% of cases of KD develop coronary ectasia or aneurysms with risk of acute myocardial infarction and sudden death. In this work we will review clinical manifestations, diagnostic criteria, differential diagnosis, therapy and predictive markers of non response immunoglobulins. We also present data of a retrospective study of children diagnosed in our center from January 2002 to December 2012.