Hiperrespuesta bronquial a la metacolina en niños menores de 4 años con bronquitis de repetición

Nicolás Cobos Barroso, Alba Torrent Vernetta, Santos Liñán Cortés, Inés de Mir Messa*, Carlos Martín de Vicente, Sandra Rovira Amigo, Antonio Moreno Galdó, Sílvia Gartner

*Autor corresponent d’aquest treball

Producció científica: Contribució a revistaArticleRecercaAvaluat per experts

3 Cites (Scopus)

Resum

Objective: To evaluate bronchial hyperresponsiveness in children under 4 years of age with recurrent wheezing bronchitis, and to determine if its presence or absence can predict the subsequent progression to a transient or persistent wheezing bronchitis phenotype. Population and methods: A bronchial challenge test was performed with methacholine using a modified tidal volume method, without sedation in a group of patients from 8 to 47 months of age with recurrent wheezing bronchitis and a control group of healthy children. A decrease in oxygen saturation of ≥5% or an increase in respiration rate of >50% [PCwheeze (PCw)] was considered a positive response. The patients were subsequently clinically followed up to assess their progress. Results: A total of 63 patients and 16 controls were studied (mean age 23.9 vs. 25.2 months). The PCw was lower than the control group (≥4. mg/ml) in 43 (68%) children from the bronchitis group (P
Títol traduït de la contribucióBronchial Hyperresponsiveness to Methacholine in Children Under 4 Years with Recurrent Bronchitis
Idioma originalEspanyol
Pàgines (de-a)621-627
Nombre de pàgines7
RevistaArchivos de bronconeumologia
Volum46
Número12
DOIs
Estat de la publicacióPublicada - de des. 2010

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