High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement

M. Montero; M. Mir; E. Sulleiro; J. L. Avalos Esquivel; E. García López; D. Molina-Morant; I. López Montesinos; L. Sorlí; G. Veliz Espinosa; E. Mounteis Oliva; M. Crespo; I. Monge; J. P. Horcajada; S. Grau; J. Pascual

doi:10.1016/j.ijid.2018.10.014

High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement

M. Montero, M. Mir, E. Sulleiro, J. L. Avalos Esquivel, E. García López, D. Molina-Morant, I. López Montesinos, L. Sorlí, G. Veliz Espinosa, E. Mounteis Oliva, M. Crespo, I. Monge, J. P. Horcajada, S. Grau, J. Pascual

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Resum

© 2018 The Authors There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.

Idioma original	Anglès
Pàgines (de-a)	103-106
Nombre de pàgines	4
Revista	International Journal of Infectious Diseases
Volum	78
DOIs	https://doi.org/10.1016/j.ijid.2018.10.014
Estat de la publicació	Publicada - 1 de gen. 2019

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Aquest resultat contribueix als següents objectius de desenvolupament sostenible.

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10.1016/j.ijid.2018.10.014

https://ddd.uab.cat/record/222757

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http://www.mendeley.com/research/highdose-benznidazole-62yearold-bolivian-kidney-transplant-recipient-chagas-central-nervous-system-i

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Montero, M., Mir, M., Sulleiro, E., Avalos Esquivel, J. L., García López, E., Molina-Morant, D., López Montesinos, I., Sorlí, L., Veliz Espinosa, G., Mounteis Oliva, E., Crespo, M., Monge, I., Horcajada, J. P., Grau, S., & Pascual, J. (2019). High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement. International Journal of Infectious Diseases, 78, 103-106. https://doi.org/10.1016/j.ijid.2018.10.014

@article{10a97ef957ca4f5fb91a584ef202b016,

title = "High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement",

abstract = "{\textcopyright} 2018 The Authors There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.",

keywords = "Benznidazole PK/PD, Benznidazole dose, Chagas disease, Chagoma, Kidney transplant recipient",

author = "M. Montero and M. Mir and E. Sulleiro and {Avalos Esquivel}, {J. L.} and {Garc{\'i}a L{\'o}pez}, E. and D. Molina-Morant and {L{\'o}pez Montesinos}, I. and L. Sorl{\'i} and {Veliz Espinosa}, G. and {Mounteis Oliva}, E. and M. Crespo and I. Monge and Horcajada, {J. P.} and S. Grau and J. Pascual",

year = "2019",

month = jan,

day = "1",

doi = "10.1016/j.ijid.2018.10.014",

language = "English",

volume = "78",

pages = "103--106",

journal = "International Journal of Infectious Diseases",

issn = "1201-9712",

publisher = "Elsevier",

}

Montero, M, Mir, M, Sulleiro, E, Avalos Esquivel, JL, García López, E, Molina-Morant, D, López Montesinos, I, Sorlí, L, Veliz Espinosa, G, Mounteis Oliva, E, Crespo, M, Monge, I, Horcajada, JP, Grau, S & Pascual, J 2019, 'High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement', International Journal of Infectious Diseases, vol. 78, pàg. 103-106. https://doi.org/10.1016/j.ijid.2018.10.014

TY - JOUR

T1 - High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement

AU - Montero, M.

AU - Mir, M.

AU - Sulleiro, E.

AU - Avalos Esquivel, J. L.

AU - García López, E.

AU - Molina-Morant, D.

AU - López Montesinos, I.

AU - Sorlí, L.

AU - Veliz Espinosa, G.

AU - Mounteis Oliva, E.

AU - Crespo, M.

AU - Monge, I.

AU - Horcajada, J. P.

AU - Grau, S.

AU - Pascual, J.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - © 2018 The Authors There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.

AB - © 2018 The Authors There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.

KW - Benznidazole PK/PD

KW - Benznidazole dose

KW - Chagas disease

KW - Chagoma

KW - Kidney transplant recipient

UR - http://www.mendeley.com/research/highdose-benznidazole-62yearold-bolivian-kidney-transplant-recipient-chagas-central-nervous-system-i

U2 - 10.1016/j.ijid.2018.10.014

DO - 10.1016/j.ijid.2018.10.014

M3 - Article

C2 - 30391324

SN - 1201-9712

VL - 78

SP - 103

EP - 106

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

ER -

High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement

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