TY - JOUR
T1 - Genomic-wide analysis approach revealed genomic similarity for environmental Mexican S. Oranienburg genomes
AU - Aguirre-Sanchez, J. R.
AU - Vega-Lopez, I. F.
AU - Castro Del Campo, N.
AU - medrano-Felix, J. A.
AU - Martínez-Urtaza, J.
AU - Chaidez-Quiroz, C.
N1 - Publisher Copyright:
© 2023 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2023/3/22
Y1 - 2023/3/22
N2 - As the human population grows, an increase in food trade is needed. This elevates the risk of epidemiological outbreaks. One of the prevalent pathogens associated with food production in Mexico has been Salmonella Oranienburg. Effective surveillance systems require microbial genetic knowledge. The objective of this work is to describe the genetic composition of Mexican S. Oranienburg genomes. For that, 53 strains from different environmental sources were isolated and sequenced. Additionally, 109 S. Oranienburg genomes were downloaded. Bioinformatic analyses were used to explore the clonal complex and genomic relatedness. A major clonal group formed by ST23 was identified comprising four STs. 202 SNPs were found the maximum difference among isolates. Virulence genes for host invasion and colonization as rpoS, fimbria type 1, and, T3SS were found common for all isolates. This study suggests that Mexican S. Oranienburg strains are potential pathogens circulating continuously in the region between host and non-host environments.
AB - As the human population grows, an increase in food trade is needed. This elevates the risk of epidemiological outbreaks. One of the prevalent pathogens associated with food production in Mexico has been Salmonella Oranienburg. Effective surveillance systems require microbial genetic knowledge. The objective of this work is to describe the genetic composition of Mexican S. Oranienburg genomes. For that, 53 strains from different environmental sources were isolated and sequenced. Additionally, 109 S. Oranienburg genomes were downloaded. Bioinformatic analyses were used to explore the clonal complex and genomic relatedness. A major clonal group formed by ST23 was identified comprising four STs. 202 SNPs were found the maximum difference among isolates. Virulence genes for host invasion and colonization as rpoS, fimbria type 1, and, T3SS were found common for all isolates. This study suggests that Mexican S. Oranienburg strains are potential pathogens circulating continuously in the region between host and non-host environments.
KW - epidemiology
KW - genome comparison
KW - S. Oranienburg
KW - Sequence Type (ST)
KW - SNP
KW - Genomics
KW - Humans
KW - Mexico
UR - https://www.scopus.com/pages/publications/85150872476
UR - https://www.mendeley.com/catalogue/ada39ad5-bb79-3af3-833c-566453ca514b/
UR - https://portalrecerca.uab.cat/en/publications/d1855499-1f7c-418e-91dc-2635e1b56fea
U2 - 10.1080/09603123.2023.2191312
DO - 10.1080/09603123.2023.2191312
M3 - Article
C2 - 36946386
AN - SCOPUS:85150872476
SN - 0960-3123
VL - 34
SP - 956
EP - 967
JO - International Journal of Environmental Health Research
JF - International Journal of Environmental Health Research
IS - 2
ER -
