Fragile sites, chromosome evolution, and human neoplasia

Rosa Miró, Inmaculada Concepción Clemente, Carmen Fuster, José Egozcue

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Resum

In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. © 1987 Springer-Verlag.
Idioma originalAnglès
Pàgines (de-a)345-349
RevistaHuman Genetics
Volum75
Número4
DOIs
Estat de la publicacióPublicada - 1 d’abr. 1987

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