TY - JOUR
T1 - Flow Injection Amperometric Determination of Pharmaceuticals
AU - González, F.
AU - Tarin, P.
AU - Maspoch Andres, Santiago
AU - Blanco Romia, Marcel
PY - 1988/1/1
Y1 - 1988/1/1
N2 - A new method is proposed for the flow injection determination of nicardipine and OPAP, [N‐(2‐oxo‐1‐pyrrolidinyl)‐acetyl]‐N′‐(3‐phenylprop‐2‐en‐2‐yl)piperazine, with amperometric detection at a fixed potential by oxidation on a glassy carbon electrode. The influence of the injected volume, flow rate, pH and electrolyte composition on the sensitivity is studied. In the proposed method, the effect of the analyte adsorption on the electrode surface is overcome. The response is linear over the range 0.3–50 mg/L for OPAP and 0.2–16 mg/L for nicardipine, their respective detection limits being 0.1 and 0.05 mg/L. Copyright © 1988 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
AB - A new method is proposed for the flow injection determination of nicardipine and OPAP, [N‐(2‐oxo‐1‐pyrrolidinyl)‐acetyl]‐N′‐(3‐phenylprop‐2‐en‐2‐yl)piperazine, with amperometric detection at a fixed potential by oxidation on a glassy carbon electrode. The influence of the injected volume, flow rate, pH and electrolyte composition on the sensitivity is studied. In the proposed method, the effect of the analyte adsorption on the electrode surface is overcome. The response is linear over the range 0.3–50 mg/L for OPAP and 0.2–16 mg/L for nicardipine, their respective detection limits being 0.1 and 0.05 mg/L. Copyright © 1988 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
UR - https://www.scopus.com/pages/publications/0023719157
U2 - 10.1002/ardp.19883211005
DO - 10.1002/ardp.19883211005
M3 - Article
SN - 0365-6233
VL - 321
SP - 725
EP - 728
JO - Archiv der Pharmazie
JF - Archiv der Pharmazie
IS - 10
ER -