TY - JOUR
T1 - Field dynamics in atrioventricular activation. Clinical evidence of a specific field-to-protein interaction
AU - Ballester-Rodés, Manel
AU - Carreras-Costa, Francesc
AU - Versyp-Ducaju, Teresa
AU - Ballester-Rodés, Montserrat
AU - Mehta, Davendra
N1 - Copyright © 2019 Elsevier Ltd. All rights reserved.
PY - 2019/3/1
Y1 - 2019/3/1
N2 - © 2019 The atrioventricular node (AV) is considered the electrical connection between the atria and ventricles. There is an electrical pause between activation of the atria and the ventricles (PR segment), but to date the mechanism responsible for this interruption remains unclear. The present communication focuses on the hypothesis that magnetic field dynamics could provide the answer. Proof of this hypothesis is that in Wolff-Parkinson-White syndrome, where there is physical connection between the atria and ventricles (bundle of Kent), there is electrical AV continuity, no PR segment is detected, and catheter ablation of the abnormal bundle restores AV discontinuity. Spontaneous initiation of the heart at the level of the sinus node, the pacemaker of the heart, could also be explained via field dynamics. The known transmembrane pacemaker protein CHN4, present in both sinoatrial and AV nodal cells, could interact with field information to provide specificity in an electronic key-to-lock mechanism interaction.
AB - © 2019 The atrioventricular node (AV) is considered the electrical connection between the atria and ventricles. There is an electrical pause between activation of the atria and the ventricles (PR segment), but to date the mechanism responsible for this interruption remains unclear. The present communication focuses on the hypothesis that magnetic field dynamics could provide the answer. Proof of this hypothesis is that in Wolff-Parkinson-White syndrome, where there is physical connection between the atria and ventricles (bundle of Kent), there is electrical AV continuity, no PR segment is detected, and catheter ablation of the abnormal bundle restores AV discontinuity. Spontaneous initiation of the heart at the level of the sinus node, the pacemaker of the heart, could also be explained via field dynamics. The known transmembrane pacemaker protein CHN4, present in both sinoatrial and AV nodal cells, could interact with field information to provide specificity in an electronic key-to-lock mechanism interaction.
KW - Atria
KW - Atrioventricular delay
KW - Atrioventricular node
KW - AV conduction
KW - Cardiac pacemaker
KW - Cardiology
KW - ECG
KW - Electrocardiogram
KW - Electromagnetism
KW - Fields
KW - Heart
KW - Preexcitation
KW - Quantum fields
KW - Sinus node
KW - Ventricles
KW - Wolff-Parkinson-White
KW - Heart Ventricles/physiopathology
KW - Humans
KW - Electrophysiology
KW - Catheter Ablation
KW - Heart Conduction System/physiopathology
KW - Atrioventricular Node/physiopathology
KW - Electrocardiography
KW - Heart Atria/physiopathology
KW - Wolff-Parkinson-White Syndrome/diagnosis
KW - Sinoatrial Node/physiopathology
KW - Arrhythmias, Cardiac/physiopathology
UR - http://www.mendeley.com/research/field-dynamics-atrioventricular-activation-clinical-evidence-specific-fieldtoprotein-interaction
UR - https://www.scopus.com/pages/publications/85061000893
U2 - 10.1016/j.mehy.2019.02.012
DO - 10.1016/j.mehy.2019.02.012
M3 - Article
C2 - 30798917
SN - 0306-9877
VL - 124
SP - 56
EP - 59
JO - Medical Hypotheses
JF - Medical Hypotheses
ER -