Fatigue in inflammatory bowel diseases: Relationship with age and disease activity

Gianluca Pellino; Guido Sciaudone; Violetta Caserta; Giuseppe Candilio; G. Serena De Fatico; Silvana Gagliardi; Isabella Landino; Marta Patturelli; Gabriele Riegler; Ester Livia Di Caprio; Silvestro Canonico; Paolo Gritti; Francesco Selvaggi

doi:10.1016/j.ijsu.2014.08.379

Fatigue in inflammatory bowel diseases: Relationship with age and disease activity

Gianluca Pellino, Guido Sciaudone, Violetta Caserta, Giuseppe Candilio, G. Serena De Fatico, Silvana Gagliardi, Isabella Landino, Marta Patturelli, Gabriele Riegler, Ester Livia Di Caprio, Silvestro Canonico, Paolo Gritti, Francesco Selvaggi^*

^*Autor corresponent d’aquest treball

Departament de Cirurgia

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

22 Cites (Scopus)

Resum

A higher rate of patients suffering from inflammatory bowel diseases (IBD) are reported to experience the symptom of fatigue compared with general population. Fatigue can impair quality of life of IBD patients by limiting their daily functioning. However, this problem is poorly understood and addressed. Our aim was to investigate the impact of fatigue in IBD patients compared with controls, and to seek for relation between age and disease activity. IBD patients aged between 16 and 75 years observed at our Unit from June 2011 through June 2012 were evaluated for fatigue. Patients were asked to fill the fatigue impact scale (FIS) questionnaire. A cohort of age- and sex-matched patients observed for other-than-IBD diseases were prospectively enrolled to act as controls. Patients diagnosed with malignancies were excluded from evaluation. Each group included 16 patients, of whom half aged over 65 years. Fatigue was more severe in IBD patients than in controls (p=0.02), irrespective of age and disease activity. IBD patients with moderate to severe disease activity showed worse fatigue compared with controls at any age (p

Idioma original	Anglès
Pàgines (de-a)	S60-S63
Revista	International Journal of Surgery
Volum	12
Número	S2
DOIs	https://doi.org/10.1016/j.ijsu.2014.08.379
Estat de la publicació	Publicada - 1 d’oct. 2014

Accés al document

10.1016/j.ijsu.2014.08.379Llicència: C In Copyright

Altres arxius i enllaços

Link to publication in Scopus

Com citar-ho

Pellino, G., Sciaudone, G., Caserta, V., Candilio, G., De Fatico, G. S., Gagliardi, S., Landino, I., Patturelli, M., Riegler, G., Di Caprio, E. L., Canonico, S., Gritti, P., & Selvaggi, F. (2014). Fatigue in inflammatory bowel diseases: Relationship with age and disease activity. International Journal of Surgery, 12(S2), S60-S63. https://doi.org/10.1016/j.ijsu.2014.08.379

@article{1b8cbaafa5634305a6b28042fa909136,

title = "Fatigue in inflammatory bowel diseases: Relationship with age and disease activity",

abstract = "A higher rate of patients suffering from inflammatory bowel diseases (IBD) are reported to experience the symptom of fatigue compared with general population. Fatigue can impair quality of life of IBD patients by limiting their daily functioning. However, this problem is poorly understood and addressed. Our aim was to investigate the impact of fatigue in IBD patients compared with controls, and to seek for relation between age and disease activity. IBD patients aged between 16 and 75 years observed at our Unit from June 2011 through June 2012 were evaluated for fatigue. Patients were asked to fill the fatigue impact scale (FIS) questionnaire. A cohort of age- and sex-matched patients observed for other-than-IBD diseases were prospectively enrolled to act as controls. Patients diagnosed with malignancies were excluded from evaluation. Each group included 16 patients, of whom half aged over 65 years. Fatigue was more severe in IBD patients than in controls (p=0.02), irrespective of age and disease activity. IBD patients with moderate to severe disease activity showed worse fatigue compared with controls at any age (p<0.0001). Young IBD patients with low disease activity showed a trend toward worse FIS score when compared with old IBD counterparts (p=0.06).IBD significantly impacted on fatigue in our series. Considering IBD patients in remission, younger patients may experience worse fatigue. Further studies are needed to explore the effects of fatigue on quality of life and the potential of appropriate intervention strategies.",

keywords = "CD, Crohn's disease, Fatigue, FIS, Inflammatory bowel diseases, Quality of life, UC, Ulcerative colitis",

author = "Gianluca Pellino and Guido Sciaudone and Violetta Caserta and Giuseppe Candilio and {De Fatico}, {G. Serena} and Silvana Gagliardi and Isabella Landino and Marta Patturelli and Gabriele Riegler and {Di Caprio}, {Ester Livia} and Silvestro Canonico and Paolo Gritti and Francesco Selvaggi",

note = "Publisher Copyright: {\textcopyright} 2014 Surgical Associates Ltd.",

year = "2014",

month = oct,

day = "1",

doi = "10.1016/j.ijsu.2014.08.379",

language = "English",

volume = "12",

pages = "S60--S63",

journal = "International Journal of Surgery",

issn = "1743-9191",

publisher = "Elsevier BV",

number = "S2",

}

Pellino, G, Sciaudone, G, Caserta, V, Candilio, G, De Fatico, GS, Gagliardi, S, Landino, I, Patturelli, M, Riegler, G, Di Caprio, EL, Canonico, S, Gritti, P & Selvaggi, F 2014, 'Fatigue in inflammatory bowel diseases: Relationship with age and disease activity', International Journal of Surgery, vol. 12, núm. S2, pàg. S60-S63. https://doi.org/10.1016/j.ijsu.2014.08.379

TY - JOUR

T1 - Fatigue in inflammatory bowel diseases

T2 - Relationship with age and disease activity

AU - Pellino, Gianluca

AU - Sciaudone, Guido

AU - Caserta, Violetta

AU - Candilio, Giuseppe

AU - De Fatico, G. Serena

AU - Gagliardi, Silvana

AU - Landino, Isabella

AU - Patturelli, Marta

AU - Riegler, Gabriele

AU - Di Caprio, Ester Livia

AU - Canonico, Silvestro

AU - Gritti, Paolo

AU - Selvaggi, Francesco

PY - 2014/10/1

Y1 - 2014/10/1

N2 - A higher rate of patients suffering from inflammatory bowel diseases (IBD) are reported to experience the symptom of fatigue compared with general population. Fatigue can impair quality of life of IBD patients by limiting their daily functioning. However, this problem is poorly understood and addressed. Our aim was to investigate the impact of fatigue in IBD patients compared with controls, and to seek for relation between age and disease activity. IBD patients aged between 16 and 75 years observed at our Unit from June 2011 through June 2012 were evaluated for fatigue. Patients were asked to fill the fatigue impact scale (FIS) questionnaire. A cohort of age- and sex-matched patients observed for other-than-IBD diseases were prospectively enrolled to act as controls. Patients diagnosed with malignancies were excluded from evaluation. Each group included 16 patients, of whom half aged over 65 years. Fatigue was more severe in IBD patients than in controls (p=0.02), irrespective of age and disease activity. IBD patients with moderate to severe disease activity showed worse fatigue compared with controls at any age (p<0.0001). Young IBD patients with low disease activity showed a trend toward worse FIS score when compared with old IBD counterparts (p=0.06).IBD significantly impacted on fatigue in our series. Considering IBD patients in remission, younger patients may experience worse fatigue. Further studies are needed to explore the effects of fatigue on quality of life and the potential of appropriate intervention strategies.

AB - A higher rate of patients suffering from inflammatory bowel diseases (IBD) are reported to experience the symptom of fatigue compared with general population. Fatigue can impair quality of life of IBD patients by limiting their daily functioning. However, this problem is poorly understood and addressed. Our aim was to investigate the impact of fatigue in IBD patients compared with controls, and to seek for relation between age and disease activity. IBD patients aged between 16 and 75 years observed at our Unit from June 2011 through June 2012 were evaluated for fatigue. Patients were asked to fill the fatigue impact scale (FIS) questionnaire. A cohort of age- and sex-matched patients observed for other-than-IBD diseases were prospectively enrolled to act as controls. Patients diagnosed with malignancies were excluded from evaluation. Each group included 16 patients, of whom half aged over 65 years. Fatigue was more severe in IBD patients than in controls (p=0.02), irrespective of age and disease activity. IBD patients with moderate to severe disease activity showed worse fatigue compared with controls at any age (p<0.0001). Young IBD patients with low disease activity showed a trend toward worse FIS score when compared with old IBD counterparts (p=0.06).IBD significantly impacted on fatigue in our series. Considering IBD patients in remission, younger patients may experience worse fatigue. Further studies are needed to explore the effects of fatigue on quality of life and the potential of appropriate intervention strategies.

KW - CD

KW - Crohn's disease

KW - Fatigue

KW - FIS

KW - Inflammatory bowel diseases

KW - Quality of life

KW - UC

KW - Ulcerative colitis

UR - http://www.scopus.com/inward/record.url?scp=84907993580&partnerID=8YFLogxK

U2 - 10.1016/j.ijsu.2014.08.379

DO - 10.1016/j.ijsu.2014.08.379

M3 - Article

C2 - 25159230

AN - SCOPUS:84907993580

SN - 1743-9191

VL - 12

SP - S60-S63

JO - International Journal of Surgery

JF - International Journal of Surgery

IS - S2

ER -

Fatigue in inflammatory bowel diseases: Relationship with age and disease activity

Resum

Accés al document

Altres arxius i enllaços

Fingerprint

Com citar-ho