Fatigue in inflammatory bowel diseases: Relationship with age and disease activity

Gianluca Pellino, Guido Sciaudone, Violetta Caserta, Giuseppe Candilio, G. Serena De Fatico, Silvana Gagliardi, Isabella Landino, Marta Patturelli, Gabriele Riegler, Ester Livia Di Caprio, Silvestro Canonico, Paolo Gritti, Francesco Selvaggi*

*Autor corresponent d’aquest treball

Producció científica: Contribució a una revistaArticleRecercaAvaluat per experts

19 Cites (Scopus)


A higher rate of patients suffering from inflammatory bowel diseases (IBD) are reported to experience the symptom of fatigue compared with general population. Fatigue can impair quality of life of IBD patients by limiting their daily functioning. However, this problem is poorly understood and addressed. Our aim was to investigate the impact of fatigue in IBD patients compared with controls, and to seek for relation between age and disease activity. IBD patients aged between 16 and 75 years observed at our Unit from June 2011 through June 2012 were evaluated for fatigue. Patients were asked to fill the fatigue impact scale (FIS) questionnaire. A cohort of age- and sex-matched patients observed for other-than-IBD diseases were prospectively enrolled to act as controls. Patients diagnosed with malignancies were excluded from evaluation. Each group included 16 patients, of whom half aged over 65 years. Fatigue was more severe in IBD patients than in controls (p=0.02), irrespective of age and disease activity. IBD patients with moderate to severe disease activity showed worse fatigue compared with controls at any age (p
Idioma originalEnglish
Pàgines (de-a)S60-S63
RevistaInternational Journal of Surgery
Estat de la publicacióPublicada - 1 d’oct. 2014


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