TY - JOUR
T1 - Executive summary of the recommendations on the evaluation and management of renal disease in human immunodeficiency virus-infected patients
AU - Trullàs, Joan C.
AU - Rivero, Antonio
AU - Gràcia, Sílvia
AU - Sanz, José
AU - Quereda, Carlos
AU - Cofán, Frederic
AU - Martínez-Castelao, Alberto
AU - Montañés, Rosario
AU - Galindo, María J.
AU - Gorriz, José L.
AU - Miró, José M.
AU - Estrada, Vicente
AU - Martínez, Esteban
AU - Miralles, Celia
AU - Santamaría, Juan M.
AU - Mazuecos, Maria A.
AU - Sanz, Jesús
AU - Arazo, Piedad
AU - Praga, Manuel
AU - Pérez-Elías, María J.
AU - Fulladosa, Xavier
AU - Iribarren, José A.
AU - Gutiérrez, Félix
AU - Negredo, Eugenia
AU - Barril, Guillermina
AU - Lozano, Fernando
AU - Portilla, Joaquín
AU - Palacios, Rosario
AU - Arribas, Jose R.
AU - Cervero, Miguel
AU - López-Aldeguer, José
AU - Domingo, Pere
AU - Knobel, Hernando
PY - 2014/11/1
Y1 - 2014/11/1
N2 - © 2014 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved. The aim of this article is to update the 2010 recommendations on the evaluation and management of renal disease in human immunodeficiency virus (HIV)-infected patients. Renal function should be monitored in all HIV-infected patients. The basic renal work-up should include measurements of serum creatinine, estimated glomerular filtration rate by CKD-EPI, urine protein-to-creatinine ratio, and urinary sediment. Tubular function tests should include determination of serum phosphate levels and urine dipstick for glycosuria. In the absence of abnormal values, renal screening should be performed annually. In patients treated with tenofovir, or with risk factors for chronic kidney disease (CKD), more frequent renal screening is recommended. In order to prevent disease progression, potentially nephrotoxic antiretroviral drugs are not recommended in patients with CKD or risk factors for CKD. The document provides indications for renal biopsy and advises on the optimal time for referral of a patient to the nephrologist. The indications for and evaluation and management of dialysis and renal transplantation are also addressed.
AB - © 2014 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved. The aim of this article is to update the 2010 recommendations on the evaluation and management of renal disease in human immunodeficiency virus (HIV)-infected patients. Renal function should be monitored in all HIV-infected patients. The basic renal work-up should include measurements of serum creatinine, estimated glomerular filtration rate by CKD-EPI, urine protein-to-creatinine ratio, and urinary sediment. Tubular function tests should include determination of serum phosphate levels and urine dipstick for glycosuria. In the absence of abnormal values, renal screening should be performed annually. In patients treated with tenofovir, or with risk factors for chronic kidney disease (CKD), more frequent renal screening is recommended. In order to prevent disease progression, potentially nephrotoxic antiretroviral drugs are not recommended in patients with CKD or risk factors for CKD. The document provides indications for renal biopsy and advises on the optimal time for referral of a patient to the nephrologist. The indications for and evaluation and management of dialysis and renal transplantation are also addressed.
KW - Tenofovir
KW - Renal failure
KW - AIDS
KW - Chronic kidney disease
KW - Human immunodeficiency virus
KW - Renal toxicity
KW - Antiretroviral therapy
KW - Renal transplantationa
UR - https://www.scopus.com/pages/publications/84909582091
UR - https://dialnet.unirioja.es/servlet/articulo?codigo=6149450
U2 - 10.1016/j.eimc.2014.09.002
DO - 10.1016/j.eimc.2014.09.002
M3 - Article
C2 - 25303781
SN - 0213-005X
VL - 32
SP - 583
EP - 597
JO - Enfermedades Infecciosas y Microbiologia Clinica
JF - Enfermedades Infecciosas y Microbiologia Clinica
IS - 9
ER -
