Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

N. Xamena; A. Creus; R. Marcos

doi:10.1016/0027-5107(85)90025-9

Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

N. Xamena, A. Creus, R. Marcos

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The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.

Idioma original	Anglès
Pàgines (de-a)	189-192
Revista	Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volum	149
DOIs	https://doi.org/10.1016/0027-5107(85)90025-9
Estat de la publicació	Publicada - 1 de gen. 1985

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10.1016/0027-5107(85)90025-9

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https://www.scopus.com/pages/publications/0021978918

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title = "Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster",

abstract = "The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. {\textcopyright} 1985.",

author = "N. Xamena and A. Creus and R. Marcos",

year = "1985",

month = jan,

day = "1",

doi = "10.1016/0027-5107(85)90025-9",

language = "English",

volume = "149",

pages = "189--192",

journal = "Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis",

issn = "0027-5107",

publisher = "Elsevier",

}

TY - JOUR

T1 - Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

AU - Xamena, N.

AU - Creus, A.

AU - Marcos, R.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.

AB - The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and translocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. © 1985.

UR - https://www.scopus.com/pages/publications/0021978918

U2 - 10.1016/0027-5107(85)90025-9

DO - 10.1016/0027-5107(85)90025-9

M3 - Article

SN - 0027-5107

VL - 149

SP - 189

EP - 192

JO - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

JF - Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

ER -

Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster

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