DNA copy number changes and evaluation of MYC, IGF1R, and FES amplification in xenografts of pancreatic adenocarcinoma

Keyphrases

• 6q24 33%
• 8q24 66%
• Aberrations 33%
• Allelic Imbalance 33%
• Cancer Progression 33%
• Centromere 33%
• Chromosome 18 33%
• Chromosome 8 33%
• Comparative Genomic Hybridization 66%
• Fluorescence in Situ Hybridization Analysis 33%
• Gene Copy number 33%
• Gene Copy number Variation 100%
• High-level Amplifications 33%
• In(III) 33%
• Informative Loci 33%
• Insulin-like Growth Factor 1 Receptor (IGF1R) 100%
• Loss of Heterozygosity 33%
• Metastasis 66%
• Oncogene 33%
• Pancreatic Adenocarcinoma 100%
• Pancreatic Tumor 66%
• Southern Analysis 66%
• Tumor 100%
• Xenograft 100%

Biochemistry, Genetics and Molecular Biology

• Allelic Imbalance 50%
• Centromere 50%
• Chromosome 18 50%
• Chromosome 8 50%
• Comparative Genomic Hybridization 100%
• Fluorescence in Situ Hybridization 50%
• Gene Dosage 100%
• Loss of Heterozygosity 50%
• Oncogene 50%