TY - JOUR
T1 - Discussion on the indication of allogeneic stem cell transplantation for advanced cutaneous T cell lymphomas
AU - Novelli, Silvana
AU - Monter, Anna
AU - Pilar García-Muret, M.
AU - Martino, Rodrigo
AU - Briones, Javier
AU - Sierra, Jorge
PY - 2019/10/1
Y1 - 2019/10/1
N2 - © 2019, Japanese Society of Hematology. Advanced cutaneous T cell lymphoma (CTCL) patients have a dismal prognosis, especially those relapsing or progressing after systemic therapy. No curative therapies are available, but some new agents have prolonged disease-free survival time with a good toxicity profile. Allogeneic stem cell transplantation (allo-SCT) offers the longest disease-free survival, potentially representing the best therapeutic option for eligible patients. In the present article, we discuss current evidence about allo-SCT for CTCL patients, timing, and new therapeutic options before allo-SCT, taking into account some considerations that may impact clinical outcome.
AB - © 2019, Japanese Society of Hematology. Advanced cutaneous T cell lymphoma (CTCL) patients have a dismal prognosis, especially those relapsing or progressing after systemic therapy. No curative therapies are available, but some new agents have prolonged disease-free survival time with a good toxicity profile. Allogeneic stem cell transplantation (allo-SCT) offers the longest disease-free survival, potentially representing the best therapeutic option for eligible patients. In the present article, we discuss current evidence about allo-SCT for CTCL patients, timing, and new therapeutic options before allo-SCT, taking into account some considerations that may impact clinical outcome.
KW - Allogeneic hematopoietic transplantation
KW - Cutaneous T cell lymphoma
KW - Mycosis fungoide
KW - Sézary syndrome
UR - http://www.mendeley.com/research/discussion-indication-allogeneic-stem-cell-transplantation-advanced-cutaneous-t-cell-lymphomas
U2 - 10.1007/s12185-019-02707-w
DO - 10.1007/s12185-019-02707-w
M3 - Review article
C2 - 31317515
SN - 0925-5710
VL - 110
SP - 406
EP - 410
JO - International Journal of Hematology
JF - International Journal of Hematology
IS - 4
ER -