TY - CHAP
T1 - Diffusion tensor imaging (DTI)
AU - Lope-Piedrafita, Silvia
PY - 2018/1/1
Y1 - 2018/1/1
N2 - © 2018, Springer Science+Business Media, LLC. Diffusion Tensor Imaging is an MRI technique that allows in vivo noninvasive measurement of the translational motion of water, providing information about its anisotropy (or lack of it) in different tissues. DTI has been commonly used to quantitatively measure the integrity of tissues which may be compromised by neurological disease, such as white matter tracks of the brain, which normally impart significant anisotropy to water motion in healthy brains. However, this anisotropic effect is diminished when axonal or neuronal damage is present. This chapter describes a standard protocol for DTI data acquisition in preclinical studies.
AB - © 2018, Springer Science+Business Media, LLC. Diffusion Tensor Imaging is an MRI technique that allows in vivo noninvasive measurement of the translational motion of water, providing information about its anisotropy (or lack of it) in different tissues. DTI has been commonly used to quantitatively measure the integrity of tissues which may be compromised by neurological disease, such as white matter tracks of the brain, which normally impart significant anisotropy to water motion in healthy brains. However, this anisotropic effect is diminished when axonal or neuronal damage is present. This chapter describes a standard protocol for DTI data acquisition in preclinical studies.
KW - Apparent diffusion coefficient
KW - Axial diffusivity
KW - Diffusion tensor imaging
KW - Fiber tracking
KW - Fractional anisotropy
KW - Radial diffusivity
KW - White matter
U2 - 10.1007/978-1-4939-7531-0_7
DO - 10.1007/978-1-4939-7531-0_7
M3 - Chapter
SN - 1064-3745
VL - 1718
SP - 103
EP - 116
BT - Methods in Molecular Biology
ER -