TY - JOUR
T1 - Determination of tylosin residues in different animal tissues by high performance liquid chromatography
AU - Prats, C.
AU - Francesch, R.
AU - Arboix, M.
AU - Pérez, B.
PY - 2002/1/1
Y1 - 2002/1/1
N2 - A HPLC method to determine and quantify tylosin residues from calves, pigs and poultry is reported. This procedure permitted tylosin to be separated from muscle, liver, kidney and fat after a simple extraction with chloroform or ethyl acetate under basic conditions. The analytical methodology showed a high specificity and sensitivity and an adequate precision and accuracy with a limit of quantification of 50 μg/kg. Eight calves were administered 20 mg/kg/day of tylosin for 5 days and slaughtered at 7 and 14 days post-administration. Results showed that at the 14th day tylosin levels were lower than the MRL in all target tissues. © 2002 Elsevier Science B.V. All rights reserved.
AB - A HPLC method to determine and quantify tylosin residues from calves, pigs and poultry is reported. This procedure permitted tylosin to be separated from muscle, liver, kidney and fat after a simple extraction with chloroform or ethyl acetate under basic conditions. The analytical methodology showed a high specificity and sensitivity and an adequate precision and accuracy with a limit of quantification of 50 μg/kg. Eight calves were administered 20 mg/kg/day of tylosin for 5 days and slaughtered at 7 and 14 days post-administration. Results showed that at the 14th day tylosin levels were lower than the MRL in all target tissues. © 2002 Elsevier Science B.V. All rights reserved.
KW - Tylosin
UR - https://www.scopus.com/pages/publications/0036165090
U2 - 10.1016/S0021-9673(01)01325-5
DO - 10.1016/S0021-9673(01)01325-5
M3 - Article
SN - 1570-0232
VL - 766
SP - 57
EP - 65
JO - Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
JF - Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
IS - 1
ER -