Resum
The aim of the study was to describe the epidemiologic and clinical characteristics and identify the risk factors of short-term and 1-year mortality in a recent cohort of patients with infective endocarditis (IE). From January 2008, multidisciplinary teams have prospectively collected all consecutive cases of IE, diagnosed according to the Duke criteria, in 25 Spanish hospitals. Overall, 1804 patients were diagnosed. The median age was 69 years (interquartile range, 55-77), 68.0% were men, and 37.1% of the cases were nosocomial or health care-related IE. Gram-positive microorganisms accounted for 79.3% of the episodes, followed by Gram-negative (5.2%), fungi (2.4%), anaerobes (0.9%), polymicrobial infections (1.9%), and unknown etiology (9.1%). Heart surgerywas performed in 44.2%, and in-hospital mortality was 28.8%. Risk factors for in-hospital mortality were age, previous heart surgery, cerebrovascular disease, atrial fibrillation, Staphylococcus or Candida etiology, intracardiac complications, heart failure, and septic shock. The 1-year independent risk factors for mortality were age (odds ratio [OR], 1.02), neoplasia (OR, 2.46), renal insufficiency (OR, 1.59), and heart failure (OR, 4.42). Surgery was an independent protective factor for 1-year mortality (OR, 0.44). IE remains a severe disease with a high rate of in-hospital (28.9%) and 1-year mortality (11.2%). Surgery was the only intervention that significantly reduced 1-year mortality.
| Idioma original | Anglès |
|---|---|
| Número d’article | e1816 |
| Revista | Medicine (United States) |
| Volum | 94 |
| Número | 43 |
| DOIs | |
| Estat de la publicació | Publicada - 2015 |
Accés al document
Altres arxius i enllaços
Fingerprint
Navegar pels temes de recerca de 'Current epidemiology and outcome of infective endocarditis: A multicenter, prospective, cohort study'. Junts formen un fingerprint únic.Com citar-ho
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver
}
In: Medicine (United States), Vol. 94, Núm. 43, e1816, 2015.
Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts
TY - JOUR
T1 - Current epidemiology and outcome of infective endocarditis
T2 - A multicenter, prospective, cohort study
AU - Muñoz, Patricia
AU - Kestler, Martha
AU - De Alarcón, Arístides
AU - Miro, José María
AU - Bermejo, Javier
AU - Rodríguez-Abella, Hugo
AU - Fariñas, Maria Carmen
AU - Belaustegui, Manuel Cobo
AU - Mestres, Carlos A.
AU - Llinares, Pedro
AU - Goenaga, Miguel
AU - Navas, Enrique
AU - Oteo, José Antonio
AU - Tarabini-Castellani, Paola
AU - Bouza, Emilio
AU - Sánchez, Fernando Fernández
AU - Noureddine, Marian
AU - Rosas, Gabriel
AU - De La Torre Lima, Javier
AU - Aramendi, José
AU - Bereciartua, Elena
AU - Boado, María Victoria
AU - Lázaro, Marta Campaña
AU - Goikoetxea, Josune
AU - Goiti, Juan José
AU - Hernández, José Luis
AU - Iruretagoyena, José Ramón
AU - Irurzunzuazabal, Josu
AU - Martínez, Inés
AU - Pérez, Pedro María
AU - Rodrí-Guez, Regino
AU - Voces, Roberto
AU - López, Ma Victoria García
AU - Georgieva, Radka Ivanova
AU - Solero, Manuel Márquez
AU - Bailón, Isabel Rodríguez
AU - Morales, Josefa Ruiz
AU - Cuende, Ana María
AU - Idígoras, Pedro
AU - Iribarren, José Antonio
AU - Yarza, Alberto Izaguirre
AU - Reviejo, Carlos
AU - Echeverría, Tomás
AU - Gaminde, Eduardo
AU - Goenaga, Miguer Angel
AU - Fuertes, Ana
AU - Carrasco, Rafael
AU - Climent, Vicente
AU - Llamas, Patricio
AU - Merino, Esperanza
AU - Plazas, Joaquín
AU - Reus, Sergio
AU - Álvarez, Nemesio
AU - Bravo-Ferrer, José María
AU - Regueiro, Dolores Sousa
AU - Sanchez, Efrén
AU - Castelo, Laura
AU - Cuenca, José
AU - Rey, Enrique Miguez
AU - Mayo, María Rodríguez
AU - Lomas, José Manuel
AU - Martínez, Francisco Javier
AU - Del Mar Alonso, Ma
AU - Castro, Beatriz
AU - Marrero, Dá Cil García
AU - Del Carmen Durán, Ma
AU - Gómez, Ma Antonia Miguel
AU - La Calzada, Juan
AU - Nassar, Ibrahim
AU - Ciezar, Antonio Plata
AU - Iglesias, José Ma Reguera
AU - Álvarez, Víctor Asensi
AU - Costas, Carlos
AU - De La Hera, Jesús
AU - Suárez, Jonnathan Fernández
AU - Ruiz, José Manuel García
AU - Fraile, Lisardo Iglesias
AU - Menéndez, José López
AU - Bajo, Pilar Mencia
AU - Morales, Carlos
AU - Torrico, Alfonso Moreno
AU - Palomo, Carmen
AU - Rez, Francisco Péé
AU - Rodríguez, Ángeles
AU - Telenti, Mauricio
AU - Almela, Manuel
AU - Armero, Yolanda
AU - Azqueta, Manuel
AU - Castañeda, Ximena
AU - Cervera, Carlos
AU - Falces, Carlos
AU - De La Maria, Cristina García
AU - Gatell, José M.
AU - Heras, Magda
AU - Pérez, Jaume Llopis
AU - Marco, Francesc
AU - Miró, Josemaria
AU - Mestres, Carlos A.
AU - Moreno, Asunción
AU - Ninot, Salvador
AU - Ramírez, José
AU - Sitges, Marta
AU - Paré, Carlos
AU - Pericás, Juan Manuel
AU - Eworo, Alia
AU - Cruz, Ana Fernández
AU - Del Vecchio, Marcela González
AU - Ramallo, Víctor González
AU - Marín, Mercedes
AU - Martínez-Sellés, Manuel
AU - Menárguez, Ma Cruz
AU - Rodríguez-Créixems, Marta
AU - Roda, Jorge Rodríguez
AU - Salas, Marisol
AU - Segado, Antonio
AU - Pinilla, Blanca
AU - Pinto, Ángel
AU - Valerio, Maricela
AU - Verde, Eduardo
AU - Antorrena, Isabel
AU - Vicente, José Ma Fraile
AU - Cerrada, Carlos García
AU - Guereta, Luis García
AU - Hernández, Alicia Lorenao
AU - Quirós, Alejandro Martín
AU - Moreno, Mar
AU - Paño, José Ramón
AU - Simón, Ma Angustias Quesada
AU - Rico, Mikel
AU - Dávila, Ma Ángeles Rodríguez
AU - Romero, María
AU - Rosillo, Sandra
AU - Nieto, Alicia Rico
AU - Arnaiz, Ana
AU - Berrazueta, José
AU - Bellisco, Sara
AU - Durán, Raquel
AU - Fariñas-Álvarez, Concepción
AU - Mazarrasa, Carlos Fernández
AU - Izquierdo, Rubén Gómez
AU - Rico, Claudia González
AU - Díez, José Gutiérrez
AU - Durán, Rafael Martín
AU - Pajarón, Marcos
AU - Parra, José Antonio
AU - Teira, Ramón
AU - Zarauza, Jesús
AU - Pavía, Pablo García
AU - González, Jesús
AU - Orden, Beatriz
AU - Ramos, Antonio
AU - González, Elena Rodríguez
AU - Centella, Tomasa
AU - Hermida, José
AU - Moya, José
AU - Martínez, Pilar
AU - Oliva, Enrique
AU - Del Río, Alejandro
AU - Ruiz, Soledad
AU - Martínez, César
AU - Nodar, Andrés
AU - Pérez, Roberto
AU - Vasallo, Francisco José
AU - Tenorio, Carmen Hidalgo
AU - De Castro, Antonio
AU - De Cueto, Marina
AU - Gallego, Pastora
AU - Baño, Jesús Rodríguez
AU - García, Emilio
AU - Haro, Juan Luis
AU - Lepe, José Antonio
AU - López, Francisco
AU - Luque, Rafael
AU - Alonso, Luis Javier
AU - Blanco, José Ramón
AU - García, Lara
AU - De Benito, Natividad
AU - Gurguí, Mercé
AU - Pacho, Cristina
AU - Pericas, Roser
AU - Pons, Guillem
AU - Álvarez, M.
AU - Fernández, A. L.
AU - Martínez, Amparo
AU - Prieto, A.
AU - Regueiro, Benito
AU - Tijeira, E.
AU - Vega, Marino
AU - Blasco, Andrés Canut
AU - Mollar, José Cordo
AU - Arana, Juan Carlos Gainzarain
AU - Uriarte, Oscar García
AU - López, Alejandro Martín
AU - De Zárate, Zuriñe Ortiz
AU - Matos, José Antonio Urturi
AU - Nacle, Ma Belén
AU - Sánchez, Antonio
AU - Vallejo, Luis
AU - Leal, José Ma Arribas
AU - Vázquez, Elisa García
AU - Torres, Alicia Hernández
AU - Gómez, Joaquín Ruiz
AU - De La Morena Valenzuela, Gonzalo
AU - Bayón, Nicolás
AU - Díaz, Ma Dolores
AU - Durán, Darío
AU - Rodríguez, Juan Carlos
AU - Moreno, Antonio
AU - Alonso, Ángel
AU - Aramburu, Javier
AU - Calvo, Felicitas Elena
AU - Rodríguez, Anai Moreno
AU - Tarabini-Castellani, Paola
N1 - Publisher Copyright: Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2015
Y1 - 2015
N2 - The aim of the study was to describe the epidemiologic and clinical characteristics and identify the risk factors of short-term and 1-year mortality in a recent cohort of patients with infective endocarditis (IE). From January 2008, multidisciplinary teams have prospectively collected all consecutive cases of IE, diagnosed according to the Duke criteria, in 25 Spanish hospitals. Overall, 1804 patients were diagnosed. The median age was 69 years (interquartile range, 55-77), 68.0% were men, and 37.1% of the cases were nosocomial or health care-related IE. Gram-positive microorganisms accounted for 79.3% of the episodes, followed by Gram-negative (5.2%), fungi (2.4%), anaerobes (0.9%), polymicrobial infections (1.9%), and unknown etiology (9.1%). Heart surgerywas performed in 44.2%, and in-hospital mortality was 28.8%. Risk factors for in-hospital mortality were age, previous heart surgery, cerebrovascular disease, atrial fibrillation, Staphylococcus or Candida etiology, intracardiac complications, heart failure, and septic shock. The 1-year independent risk factors for mortality were age (odds ratio [OR], 1.02), neoplasia (OR, 2.46), renal insufficiency (OR, 1.59), and heart failure (OR, 4.42). Surgery was an independent protective factor for 1-year mortality (OR, 0.44). IE remains a severe disease with a high rate of in-hospital (28.9%) and 1-year mortality (11.2%). Surgery was the only intervention that significantly reduced 1-year mortality.
AB - The aim of the study was to describe the epidemiologic and clinical characteristics and identify the risk factors of short-term and 1-year mortality in a recent cohort of patients with infective endocarditis (IE). From January 2008, multidisciplinary teams have prospectively collected all consecutive cases of IE, diagnosed according to the Duke criteria, in 25 Spanish hospitals. Overall, 1804 patients were diagnosed. The median age was 69 years (interquartile range, 55-77), 68.0% were men, and 37.1% of the cases were nosocomial or health care-related IE. Gram-positive microorganisms accounted for 79.3% of the episodes, followed by Gram-negative (5.2%), fungi (2.4%), anaerobes (0.9%), polymicrobial infections (1.9%), and unknown etiology (9.1%). Heart surgerywas performed in 44.2%, and in-hospital mortality was 28.8%. Risk factors for in-hospital mortality were age, previous heart surgery, cerebrovascular disease, atrial fibrillation, Staphylococcus or Candida etiology, intracardiac complications, heart failure, and septic shock. The 1-year independent risk factors for mortality were age (odds ratio [OR], 1.02), neoplasia (OR, 2.46), renal insufficiency (OR, 1.59), and heart failure (OR, 4.42). Surgery was an independent protective factor for 1-year mortality (OR, 0.44). IE remains a severe disease with a high rate of in-hospital (28.9%) and 1-year mortality (11.2%). Surgery was the only intervention that significantly reduced 1-year mortality.
UR - https://www.scopus.com/pages/publications/84946567058
U2 - 10.1097/MD.0000000000001816
DO - 10.1097/MD.0000000000001816
M3 - Article
C2 - 26512582
AN - SCOPUS:84946567058
SN - 0025-7974
VL - 94
JO - Medicine (United States)
JF - Medicine (United States)
IS - 43
M1 - e1816
ER -