Keyphrases
Cytochrome P450 (CYP450)
100%
Genetic Variability
100%
Dose-response
100%
Pharmacokinetics
100%
Dose Requirement
100%
Methadone
100%
ATP Binding Cassette Subfamily B Member 1 (ABCB1)
100%
Plasma Concentration
50%
Cytochrome P450 2D6 (CYP2D6)
50%
Methadone Maintenance Treatment
50%
Methadone Dose
50%
Non-responders
33%
Opioid Dependence
33%
Clinical Outcomes
16%
High Dose
16%
Blood Samples
16%
Between-group
16%
Allelic Variants
16%
Treatment Outcome
16%
Statistical Manual of Mental Disorders
16%
Pharmacogenetics
16%
Community-based Programs
16%
Genotype Frequency
16%
P-glycoprotein (P-gp)
16%
CYP2C9
16%
CYP2C19
16%
Opioid Consumption
16%
Opioid-dependent Patients
16%
4th Edition
16%
Urinalysis
16%
Illicit Opioids
16%
Ultrarapid Metabolizer
16%
CYP3A5
16%
Responder Status
16%
Biochemistry, Genetics and Molecular Biology
Genetic Divergence
100%
Pharmacokinetics
100%
Methadone
100%
Cytochrome P450
100%
Blood Level
25%
CYP2D6
16%
Genotyping
8%
Drug Megadose
8%
DSM-IV
8%
Pharmacogenetics
8%
CYP2C9
8%
CYP2C19
8%
P-Glycoprotein
8%
CYP3A5
8%
CYP2B6
8%
Insulin
8%
Neuroscience
Methadone
100%
Cytochrome P450
100%
Pharmacokinetics
100%
Blood Plasma
25%
Cytochrome P450 2D6
16%
Opiate
16%
Opioid Dependence
16%
Insulin
8%
Diagnostic and Statistical Manual of Mental Disorders
8%
Cytochrome P450 2C9
8%
ABC Transporter Subfamily B
8%
Cytochrome P450 2C19
8%
CYP2B6
8%
Cytochrome P450 3A5
8%
Pharmacology, Toxicology and Pharmaceutical Science
Cytochrome P450
100%
Methadone
100%
Pharmacokinetics
100%
Opiate
16%
CYP2D6
16%
Opiate Addiction
16%
P-Glycoprotein
8%
Pharmacogenetics
8%
Disease
8%
Insulin
8%
CYP2C19
8%
CYP2C9
8%
DSM-IV
8%
Cytochrome P450 3A5
8%
CYP2B6
8%