TY - JOUR
T1 - Combined pleomorphic xanthoastrocytoma-ganglioglioma with BRAF V600E mutation: Case report
AU - Cicuendez, Marta
AU - Martinez-Saez, Elena
AU - Martinez-Ricarte, Francisco
AU - Asanza, Esteban Cordero
AU - Sahuquillo, Juan
PY - 2016/7/1
Y1 - 2016/7/1
N2 - © 2016 AANS. Combined pleomorphic xanthoastrocytoma (PXA) and ganglioglioma (GG) is an extremely rare tumor, with fewer than 20 cases reported. The authors report a case of combined PXA-GG in an 18-year-old man with a history of seizures. The tumor showed necrosis and the BRAF V600E mutation on histological examination, with no evidence of tumor recurrence 1 year after gross-total resection. The BRAF V600E mutation was present, which suggests that both cell lineages may share a common cellular origin.
AB - © 2016 AANS. Combined pleomorphic xanthoastrocytoma (PXA) and ganglioglioma (GG) is an extremely rare tumor, with fewer than 20 cases reported. The authors report a case of combined PXA-GG in an 18-year-old man with a history of seizures. The tumor showed necrosis and the BRAF V600E mutation on histological examination, with no evidence of tumor recurrence 1 year after gross-total resection. The BRAF V600E mutation was present, which suggests that both cell lineages may share a common cellular origin.
KW - BRAF mutation
KW - Combined pleomorphic xanthoastrocytoma-ganglioglioma
KW - Ganglioglioma
KW - Oncology
KW - Pleomorphic xanthoastrocytoma
UR - https://www.scopus.com/pages/publications/84978976044
U2 - 10.3171/2016.1.PEDS15558
DO - 10.3171/2016.1.PEDS15558
M3 - Article
SN - 1933-0707
VL - 18
SP - 53
EP - 57
JO - Journal of Neurosurgery: Pediatrics
JF - Journal of Neurosurgery: Pediatrics
IS - 1
ER -