Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

Ming Liu; Axel Guinart Guillem; Albert Granados Toda; Carolina Gimbert Suriñach; Ester Fernandez; Roser Pleixats i Rovira; Adelina Vallribera Massó

doi:10.1021/acsami.4c00383

Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

Ming Liu, Axel Guinart Guillem, Albert Granados Toda, Carolina Gimbert Suriñach, Ester Fernandez, Roser Pleixats i Rovira, Adelina Vallribera Massó

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

9 Cites (Scopus)

Resum

Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.

Idioma original	Anglès
Pàgines (de-a)	14595-14604
Nombre de pàgines	10
Revista	ACS applied materials & interfaces
Volum	16
Número	12
DOIs	https://doi.org/10.1021/acsami.4c00383
Estat de la publicació	Publicada - 12 de març 2024

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10.1021/acsami.4c00383

https://ddd.uab.cat/record/291542

Altres arxius i enllaços

1 Acabat
2 Actiu

METODOS EMERGENTES PARA LA INTRODUCCION DE GRUPOS (PER)FLUORADOS. FOTOCATALISIS
Vallribera Masso, A. (PI), Pleixats Rovira, R. (Investigador/a), Granados Toda, A. (Investigador/a), Liu, M. Z. (Col.laborador/a) & Tan, X. (Col.laborador/a)
1/09/22 → 31/08/25
Projecte: Projectes i Ajuts a la Recerca
MOLECULAS Y MATERIALES ORGANICOS PARA REACCIONES CATALITICAS ACTIVADAS MEDIANTE LA LUZ SOLAR
Gimbert Suriñach, C. (PI), Gallego Gamo, A. (Col.laborador/a) & Sarró Grane, P. (Col.laborador/a)
1/09/22 → 31/08/25
Projecte: Projectes i Ajuts a la Recerca
QUIMICA ORGANOFLUORADA: METODOS EMERGENTES DE FLUORACION Y TEJIDOS DE ALGODON PARA USOS MEDICOS
Vallribera Masso, A. (PI), Pleixats Rovira, R. (Co-Investigador/a Principal), Fernandez Freixes, G. (Col.laborador/a), Granados Toda, A. (Col.laborador/a), Li , H. (Col.laborador/a), Liu, M. (Col.laborador/a), Gimbert Suriñach, C. (Col.laborador/a) & Gallego Gamo, A. (Col.laborador/a)
Ministerio de Economía y Competitividad (MINECO)
1/01/19 → 30/09/22
Projecte: Projectes i Ajuts a la Recerca

Com citar-ho

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title = "Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing",

abstract = "Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.",

keywords = "amide groups, anti-inflammatory, antimicrobial, cotton wound dressing, enzymatic cleavage, ibuprofen, norfloxacin, silica nanoparticles",

author = "Ming Liu and {Guinart Guillem}, Axel and {Granados Toda}, Albert and {Gimbert Suri{\~n}ach}, Carolina and Ester Fernandez and {Pleixats i Rovira}, Roser and {Vallribera Mass{\'o}}, Adelina",

note = "Publisher Copyright: {\textcopyright} 2024 The Authors. Published by American Chemical Society",

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month = mar,

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doi = "10.1021/acsami.4c00383",

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T1 - Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

AU - Liu, Ming

AU - Guinart Guillem, Axel

AU - Granados Toda, Albert

AU - Gimbert Suriñach, Carolina

AU - Fernandez, Ester

AU - Pleixats i Rovira, Roser

AU - Vallribera Massó, Adelina

PY - 2024/3/12

Y1 - 2024/3/12

N2 - Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.

AB - Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.

KW - amide groups

KW - anti-inflammatory

KW - antimicrobial

KW - cotton wound dressing

KW - enzymatic cleavage

KW - ibuprofen

KW - norfloxacin

KW - silica nanoparticles

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UR - https://www.mendeley.com/catalogue/0e8c2a92-0f3d-3fec-a1a3-b65d7bc5b023/

U2 - 10.1021/acsami.4c00383

DO - 10.1021/acsami.4c00383

M3 - Article

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SN - 1944-8252

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JO - ACS applied materials & interfaces

JF - ACS applied materials & interfaces

IS - 12

ER -

Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

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METODOS EMERGENTES PARA LA INTRODUCCION DE GRUPOS (PER)FLUORADOS. FOTOCATALISIS

MOLECULAS Y MATERIALES ORGANICOS PARA REACCIONES CATALITICAS ACTIVADAS MEDIANTE LA LUZ SOLAR

QUIMICA ORGANOFLUORADA: METODOS EMERGENTES DE FLUORACION Y TEJIDOS DE ALGODON PARA USOS MEDICOS

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