TY - JOUR
T1 - Characterization of equipment for shaping and imaging hadron minibeams
AU - Pugatch, V.
AU - Brons, S.
AU - Campbell, M.
AU - Kovalchuk, O.
AU - Llopart, X.
AU - Martínez-Rovira, I.
AU - Momot, Ie
AU - Okhrimenko, O.
AU - Prezado, Y.
AU - Sorokin, Yu
N1 - Funding Information:
The authors thank HIT (Heidelberg) personnel and FP7 (Grant Agreement No. 228436 ) for granted beam-time. We deeply acknowledge Lorena Magdallanes, Gerard Montarou and Victor Iakovenko for their help. This study was conducted in the scope of the IDEATE International Associated Laboratory (LIA). We thank MEDIPIX Collaboration for introducing us a chance to use Timepix detectors for these studies. This work has been supported by the grants of the State Fund For Fundamental Research (project F69/49-2016 ) and NAS Ukraine ( CO-1-7/2016 ).
Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/11/11
Y1 - 2017/11/11
N2 - For the feasibility studies of spatially fractionated hadron therapy prototypes of the equipment for hadron minibeams shaping and monitoring have been designed, built and tested. The collimators design was based on Monte Carlo simulations (Gate v.6.2). Slit and matrix collimators were used for minibeams shaping. Gafchromic films, micropixel detectors Timepix in a hybrid as well as metal mode were tested for measuring hadrons intensity distribution in minibeams. An overall beam profile was measured by the metal microstrip detector. The performance of a mini-beams shaping and monitoring equipment was characterized exploring low energy protons at the KINR Tandem generator as well as high energy carbon and oxygen ion beams at HIT (Heidelberg). The results demonstrate reliable performance of the tested equipment for shaping and imaging hadron mini-beam structures.
AB - For the feasibility studies of spatially fractionated hadron therapy prototypes of the equipment for hadron minibeams shaping and monitoring have been designed, built and tested. The collimators design was based on Monte Carlo simulations (Gate v.6.2). Slit and matrix collimators were used for minibeams shaping. Gafchromic films, micropixel detectors Timepix in a hybrid as well as metal mode were tested for measuring hadrons intensity distribution in minibeams. An overall beam profile was measured by the metal microstrip detector. The performance of a mini-beams shaping and monitoring equipment was characterized exploring low energy protons at the KINR Tandem generator as well as high energy carbon and oxygen ion beams at HIT (Heidelberg). The results demonstrate reliable performance of the tested equipment for shaping and imaging hadron mini-beam structures.
KW - Beam collimators
KW - Gafchromic films
KW - Monitoring of spatial distribution of hadron beams
KW - Monte Carlo simulation of dose distributions
KW - Position sensitive microdetectors
KW - Spatially fractionated hadron therapy
UR - http://www.scopus.com/inward/record.url?scp=85027840863&partnerID=8YFLogxK
U2 - 10.1016/j.nima.2017.08.007
DO - 10.1016/j.nima.2017.08.007
M3 - Article
AN - SCOPUS:85027840863
SN - 0168-9002
VL - 872
SP - 119
EP - 125
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
ER -