Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin : educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)

Amy K. Saenger, Allan S. Jaffe, Richard Body, Paul O. Collinson, Peter A. Kavsak, Carolyn S. P. Lam, Guillaume Lefèvre, Tobjørn Omland, Jorge Ordoñez Llanos, Kari Pulkki, Fred S. Apple

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Resum

Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers (IFCC-CB) obtained input from a majority of cTn and NP assay manufacturers to collate information related to high-sensitivity (hs)-cTnI, hs-cTnT, contemporary, and POC cTn assays, and NP assays interferences due to hemolysis and biotin. The information contained in these tables was designed as educational tools to aid laboratory professionals and clinicians in troubleshooting cardiac biomarker analytical results that are discordant with the clinical situation.
Idioma originalAnglès
Pàgines (de-a)633-640
Nombre de pàgines8
RevistaClinical Chemistry and Laboratory Medicine
Volum57
Número5
DOIs
Estat de la publicacióPublicada - 2019

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