Boron trifluoride-methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity

Sergey Miltsov; Vladimir Karavan; Alexandr Misharev; Julian Alonso-Chamarro; Mar Puyol

doi:10.1016/j.tetlet.2015.12.087

Boron trifluoride-methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity

Sergey Miltsov, Vladimir Karavan, Alexandr Misharev, Julian Alonso-Chamarro, Mar Puyol^*

^*Autor corresponent d’aquest treball

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© 2015 Elsevier Ltd. All rights reserved. A boron trifluoride-methanol complex demonstrated remarkable deprotection selectivity against commonly used amino-protecting groups in the deacetylation of acetanilides and high sensitivity to the steric hindrance of substrates. The scope and limitations of the reaction were explored.

Idioma original	Anglès
Pàgines (de-a)	641-644
Revista	Tetrahedron Letters
Volum	57
Número	6
DOIs	https://doi.org/10.1016/j.tetlet.2015.12.087
Estat de la publicació	Publicada - 10 de febr. 2016

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10.1016/j.tetlet.2015.12.087

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title = "Boron trifluoride-methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity",

abstract = "{\textcopyright} 2015 Elsevier Ltd. All rights reserved. A boron trifluoride-methanol complex demonstrated remarkable deprotection selectivity against commonly used amino-protecting groups in the deacetylation of acetanilides and high sensitivity to the steric hindrance of substrates. The scope and limitations of the reaction were explored.",

keywords = "Acetanilides, Boron trifluoride, Deacetylation, Deprotection",

author = "Sergey Miltsov and Vladimir Karavan and Alexandr Misharev and Julian Alonso-Chamarro and Mar Puyol",

year = "2016",

month = feb,

day = "10",

doi = "10.1016/j.tetlet.2015.12.087",

language = "English",

volume = "57",

pages = "641--644",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "6",

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TY - JOUR

T1 - Boron trifluoride-methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity

AU - Miltsov, Sergey

AU - Karavan, Vladimir

AU - Misharev, Alexandr

AU - Alonso-Chamarro, Julian

AU - Puyol, Mar

PY - 2016/2/10

Y1 - 2016/2/10

N2 - © 2015 Elsevier Ltd. All rights reserved. A boron trifluoride-methanol complex demonstrated remarkable deprotection selectivity against commonly used amino-protecting groups in the deacetylation of acetanilides and high sensitivity to the steric hindrance of substrates. The scope and limitations of the reaction were explored.

AB - © 2015 Elsevier Ltd. All rights reserved. A boron trifluoride-methanol complex demonstrated remarkable deprotection selectivity against commonly used amino-protecting groups in the deacetylation of acetanilides and high sensitivity to the steric hindrance of substrates. The scope and limitations of the reaction were explored.

KW - Acetanilides

KW - Boron trifluoride

KW - Deacetylation

KW - Deprotection

U2 - 10.1016/j.tetlet.2015.12.087

DO - 10.1016/j.tetlet.2015.12.087

M3 - Article

SN - 0040-4039

VL - 57

SP - 641

EP - 644

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 6

ER -

Boron trifluoride-methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity

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