TY - JOUR
T1 - Bone mass of a 113-year-old man
AU - Mellibovsky, Leonardo
AU - Bustamante, Mariona
AU - Lluch, Pau
AU - Nogues, Xavier
AU - Grinberg, Daniel
AU - Balcells, Susana
AU - Diez-Perez, Adolfo
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers. Copyright 2007 by The Gerontological Society of America.
AB - Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers. Copyright 2007 by The Gerontological Society of America.
UR - https://www.scopus.com/pages/publications/34548457675
U2 - 10.1093/gerona/62.7.794
DO - 10.1093/gerona/62.7.794
M3 - Article
SN - 1079-5006
VL - 62
SP - 794
EP - 795
JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
IS - 7
ER -