TY - CHAP
T1 - Biomarkers in heart failure: ST2
AU - Bayes-Genis, Antoni
AU - Lupón, Josep
PY - 2016/1/1
Y1 - 2016/1/1
N2 - © Springer International Publishing Switzerland 2016. Biomarkers have emerged as indispensable tools for diagnosis and prognosis in a variety of cardiovascular diseases, and several are now considered standard of care. New markers are constantly being developed, but very few are able to signifi- cantly improve upon already-established markers. ST2 is a marker of cardiomyocyte stress and fibrosis which provides incremental value to natriuretic peptides for risk stratification in heart failure. Based upon the totality of data, measurement of ST2 is now recommended for additive risk stratification in patients with acute or ambulatory heart failure in the 2013 ACCF/AHA Guidelines. Looking forward, ST2 levels may be useful for tailoring medical therapy and to predict ventricular reverse remodeling. This chapter provides an up-to-date overview of ST2 as a marker of heart failure, and provides illustrative clinical cases into the application of ST2 now and in the future.
AB - © Springer International Publishing Switzerland 2016. Biomarkers have emerged as indispensable tools for diagnosis and prognosis in a variety of cardiovascular diseases, and several are now considered standard of care. New markers are constantly being developed, but very few are able to signifi- cantly improve upon already-established markers. ST2 is a marker of cardiomyocyte stress and fibrosis which provides incremental value to natriuretic peptides for risk stratification in heart failure. Based upon the totality of data, measurement of ST2 is now recommended for additive risk stratification in patients with acute or ambulatory heart failure in the 2013 ACCF/AHA Guidelines. Looking forward, ST2 levels may be useful for tailoring medical therapy and to predict ventricular reverse remodeling. This chapter provides an up-to-date overview of ST2 as a marker of heart failure, and provides illustrative clinical cases into the application of ST2 now and in the future.
KW - Biomarker ST2
KW - Biomarkers in heart failure
KW - Cardiomyocyte stress and fibrosis
KW - Heart failure biomarkers
KW - Risk prediction in chronic heart failure
KW - ST2 biomarker
U2 - 10.1007/978-3-319-42982-3_21
DO - 10.1007/978-3-319-42982-3_21
M3 - Chapter
SN - 9783319429823
SN - 9783319429809
SP - 251
EP - 268
BT - Cardiac Biomarkers: Case Studies and Clinical Correlations
ER -