Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge

Martí Cortey; Gaston Arocena; Tahar Ait-Ali; Anna Vidal; Yanli Li; Gerard Martín-Valls; Alison D. Wilson; Allan L. Archibald; Enric Mateu; Laila Darwich

doi:10.1186/s13567-018-0514-1

Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge

Martí Cortey, Gaston Arocena, Tahar Ait-Ali, Anna Vidal, Yanli Li, Gerard Martín-Valls, Alison D. Wilson, Allan L. Archibald, Enric Mateu, Laila Darwich

Departament de Sanitat i d'Anatomia Animals

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© 2018 The Author(s). Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host's cellular and humoral immune response. Immunity against PRRSv is multigenic and vary between individuals. The aim of the present study was to compare several genes that encode for molecules involved in the immune response between two groups of vaccinated pigs that experienced short or long viremic periods after PRRSv challenge. These analyses include the sequencing of four SLA Class I, two Class II allele groups, and CD163, plus the analysis by quantitative realtime qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 mRNA and other molecules in peripheral blood mononuclear cells.

Idioma original	Anglès
Número d’article	19
Revista	Veterinary Research
Volum	49
DOIs	https://doi.org/10.1186/s13567-018-0514-1
Estat de la publicació	Publicada - 15 de febr. 2018

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10.1186/s13567-018-0514-1

https://ddd.uab.cat/record/187892

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Cortey, M., Arocena, G., Ait-Ali, T., Vidal, A., Li, Y., Martín-Valls, G., Wilson, A. D., Archibald, A. L., Mateu, E., & Darwich, L. (2018). Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge. Veterinary Research, 49, Article 19. https://doi.org/10.1186/s13567-018-0514-1

@article{247fcec1877347cb8ea2364270677839,

title = "Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge",

abstract = "{\textcopyright} 2018 The Author(s). Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host's cellular and humoral immune response. Immunity against PRRSv is multigenic and vary between individuals. The aim of the present study was to compare several genes that encode for molecules involved in the immune response between two groups of vaccinated pigs that experienced short or long viremic periods after PRRSv challenge. These analyses include the sequencing of four SLA Class I, two Class II allele groups, and CD163, plus the analysis by quantitative realtime qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 mRNA and other molecules in peripheral blood mononuclear cells.",

author = "Mart{\'i} Cortey and Gaston Arocena and Tahar Ait-Ali and Anna Vidal and Yanli Li and Gerard Mart{\'i}n-Valls and Wilson, {Alison D.} and Archibald, {Allan L.} and Enric Mateu and Laila Darwich",

year = "2018",

month = feb,

day = "15",

doi = "10.1186/s13567-018-0514-1",

language = "English",

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}

Cortey, M, Arocena, G, Ait-Ali, T, Vidal, A, Li, Y, Martín-Valls, G, Wilson, AD, Archibald, AL, Mateu, E & Darwich, L 2018, 'Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge', Veterinary Research, vol. 49, 19. https://doi.org/10.1186/s13567-018-0514-1

Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge. / Cortey, Martí; Arocena, Gaston; Ait-Ali, Tahar et al.
In: Veterinary Research, Vol. 49, 19, 15.02.2018.

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

TY - JOUR

T1 - Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge

AU - Cortey, Martí

AU - Arocena, Gaston

AU - Ait-Ali, Tahar

AU - Vidal, Anna

AU - Li, Yanli

AU - Martín-Valls, Gerard

AU - Wilson, Alison D.

AU - Archibald, Allan L.

AU - Mateu, Enric

AU - Darwich, Laila

PY - 2018/2/15

Y1 - 2018/2/15

N2 - © 2018 The Author(s). Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host's cellular and humoral immune response. Immunity against PRRSv is multigenic and vary between individuals. The aim of the present study was to compare several genes that encode for molecules involved in the immune response between two groups of vaccinated pigs that experienced short or long viremic periods after PRRSv challenge. These analyses include the sequencing of four SLA Class I, two Class II allele groups, and CD163, plus the analysis by quantitative realtime qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 mRNA and other molecules in peripheral blood mononuclear cells.

AB - © 2018 The Author(s). Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host's cellular and humoral immune response. Immunity against PRRSv is multigenic and vary between individuals. The aim of the present study was to compare several genes that encode for molecules involved in the immune response between two groups of vaccinated pigs that experienced short or long viremic periods after PRRSv challenge. These analyses include the sequencing of four SLA Class I, two Class II allele groups, and CD163, plus the analysis by quantitative realtime qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 mRNA and other molecules in peripheral blood mononuclear cells.

U2 - 10.1186/s13567-018-0514-1

DO - 10.1186/s13567-018-0514-1

M3 - Article

SN - 0928-4249

VL - 49

JO - Veterinary Research

JF - Veterinary Research

M1 - 19

ER -

Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge

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