TY - JOUR
T1 - Analysis of cytogenetic damage induced in cultured human lymphocytes by the pyrethroid insecticides cypermethrin and fenvalerate
AU - Puig, M.
AU - Carbonell, E.
AU - Xamena, N.
AU - Creus, A.
AU - Marcos, R.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Two pyrethroid insecticides, cypermethrin and fenvalerate, were tested for their ability to induce chromosome structural aberrations and sister chromatid exchanges in cultured human peripheral blood lymphocytes. Fenvalerate, but not cypermethrin, increased the frequencies of chromosome-type aberrations and sister chromatid exchanges. In addition, both pyrethroids affected the cell cycle causing a decrease in the proliferative rate index at concentrations > 10 μg/ml. © 1989 IRL Press Ltd.
AB - Two pyrethroid insecticides, cypermethrin and fenvalerate, were tested for their ability to induce chromosome structural aberrations and sister chromatid exchanges in cultured human peripheral blood lymphocytes. Fenvalerate, but not cypermethrin, increased the frequencies of chromosome-type aberrations and sister chromatid exchanges. In addition, both pyrethroids affected the cell cycle causing a decrease in the proliferative rate index at concentrations > 10 μg/ml. © 1989 IRL Press Ltd.
U2 - 10.1093/mutage/4.1.72
DO - 10.1093/mutage/4.1.72
M3 - Article
SN - 0267-8357
VL - 4
SP - 72
EP - 74
JO - Mutagenesis
JF - Mutagenesis
IS - 1
ER -