TY - JOUR
T1 - Absence of evidence of porcine circovirus infection in piglets with congenital tremors
AU - Kennedy, Seamus
AU - Segalés, Joaquim
AU - Rovira, Albert
AU - Scholes, Sandra
AU - Domingo, Mariano
AU - Moffett, Deborah
AU - Meehan, Brian
AU - O'Neill, Ronan
AU - McNeilly, Francis
AU - Allan, Gordon
PY - 2003/1/1
Y1 - 2003/1/1
N2 - Porcine circovirus types 1 (PCV1) and 2 (PCV2) have been associated with congenital tremors (CTs) in piglets in the United States. In this study, central nervous system and nonneural tissues of 40 CT piglets from Spain, the United Kingdom, Ireland, and Sweden were investigated for the presence of PCVl and PCV2 using in situ hybridization and immunohistochemical labeling on paraffin sections. The polymerase chain reaction for PCV2 was also carried out on sera from the Spanish CT cases. No evidence of circovirus nucleic acid or antigen was found in any CT piglet. Although these results do not support the hypothesis that PCVl or PCV2 are linked to porcine CT, they cannot disprove it.
AB - Porcine circovirus types 1 (PCV1) and 2 (PCV2) have been associated with congenital tremors (CTs) in piglets in the United States. In this study, central nervous system and nonneural tissues of 40 CT piglets from Spain, the United Kingdom, Ireland, and Sweden were investigated for the presence of PCVl and PCV2 using in situ hybridization and immunohistochemical labeling on paraffin sections. The polymerase chain reaction for PCV2 was also carried out on sera from the Spanish CT cases. No evidence of circovirus nucleic acid or antigen was found in any CT piglet. Although these results do not support the hypothesis that PCVl or PCV2 are linked to porcine CT, they cannot disprove it.
UR - https://www.scopus.com/pages/publications/0037672901
U2 - 10.1177/104063870301500209
DO - 10.1177/104063870301500209
M3 - Article
SN - 1040-6387
VL - 15
SP - 151
EP - 156
JO - Journal of Veterinary Diagnostic Investigation
JF - Journal of Veterinary Diagnostic Investigation
IS - 2
ER -