TY - CHAP
T1 - A Virtual Clinical Trial for Evaluation of Intelligent Monitoring of Exacerbation Level for COPD Patients
AU - Asghar, Mohsen Hallaj
AU - Wong, Alvaro
AU - Epelde, Francisco
AU - Taboada, Manel
AU - Rosario, Dolores Isabel Rexachs del
AU - Luque, Emilio
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.
PY - 2024/6/29
Y1 - 2024/6/29
N2 - Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition, ranking as the third leading cause of global morbidity and mortality. In this project, we simulate Real Clinical Trials using Virtual Clinical Trials (VCT) for COPD patients, offering possibilities not feasible in traditional trials, such as exploring treatment adherence levels and creating virtual cohorts with specific characteristics. We propose a cohort-based management strategy leveraging data analytics to identify patterns within the COPD patient population and advocate for employing a finite-state machine (FSM) approach to model COPD exacerbations. Further research and validation are crucial to refine and scale this integrated model.
AB - Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition, ranking as the third leading cause of global morbidity and mortality. In this project, we simulate Real Clinical Trials using Virtual Clinical Trials (VCT) for COPD patients, offering possibilities not feasible in traditional trials, such as exploring treatment adherence levels and creating virtual cohorts with specific characteristics. We propose a cohort-based management strategy leveraging data analytics to identify patterns within the COPD patient population and advocate for employing a finite-state machine (FSM) approach to model COPD exacerbations. Further research and validation are crucial to refine and scale this integrated model.
KW - Agent based modeling
KW - Finite-state machine (FSM)
KW - Self-management COPD patient
KW - virtual clinical trial
UR - https://doi.org/10.1007/978-3-031-63759-9_17
UR - http://www.scopus.com/inward/record.url?scp=85199647395&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/8e4414ea-fdb5-38bb-9323-7f7786736928/
U2 - 10.1007/978-3-031-63759-9_17
DO - 10.1007/978-3-031-63759-9_17
M3 - Chapter
SN - 978-3-031-63758-2
VL - 14834
SP - 137
EP - 144
BT - Computational Science – ICCS 2024. ICCS 2024. Lecture Notes in Computer Science
A2 - Franco, Leonardo
A2 - de Mulatier, Clélia
A2 - Paszynski, Maciej
A2 - Krzhizhanovskaya, Valeria V.
A2 - Dongarra, Jack J.
A2 - Sloot, Peter M. A.
ER -