TY - JOUR
T1 - A New Chirally Organized Trifluoromethylanthrylmethanol Derivative and Its Application as Chiral Solvating Agent
AU - Monteagudo, Eva
AU - de March, Pedro
AU - Álvarez-Larena, Ángel
AU - Virgili, Albert
PY - 2017/1/1
Y1 - 2017/1/1
N2 - © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The synthesis and structure of 1,1′-(((10,10’-(1,1′-binaphthalene)-2,2′-diylbis(oxy))bis(methylene))bis(anthracene-10,9-diyl))bis(2,2,2-trifluoroethanol), 4, is reported. This compound owns both axial and central chirality allowing its use as a chiral solvating agent (CSA) for the enantiomeric composition determination of several mixtures of chiral aromatic alcohols and amines using NMR. The study of the resulting diastereoisomeric complexes was carried out by determining its stoichiometry and association binding constants.
AB - © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The synthesis and structure of 1,1′-(((10,10’-(1,1′-binaphthalene)-2,2′-diylbis(oxy))bis(methylene))bis(anthracene-10,9-diyl))bis(2,2,2-trifluoroethanol), 4, is reported. This compound owns both axial and central chirality allowing its use as a chiral solvating agent (CSA) for the enantiomeric composition determination of several mixtures of chiral aromatic alcohols and amines using NMR. The study of the resulting diastereoisomeric complexes was carried out by determining its stoichiometry and association binding constants.
KW - BINOL
KW - Chiral Solvating Agents
KW - enantiodifferentiation
KW - NMR
KW - spectroscopy
U2 - 10.1002/slct.201701429
DO - 10.1002/slct.201701429
M3 - Article
SN - 2365-6549
VL - 2
SP - 7362
EP - 7367
JO - ChemistrySelect
JF - ChemistrySelect
IS - 24
ER -