A molecular epidemiological study of human parainfluenza virus type 3 at a tertiary university hospital during 2013–2015 in Catalonia, Spain

Cristina Godoy, Paula Peremiquel-Trillas, Cristina Andrés, Laura Gimferrer, Sonia María Uriona, María Gema Codina, Lluis Armadans, María del Carmen Martín, Francisco Fuentes, Juliana Esperalba, Magda Campins, Tomàs Pumarola, Andrés Antón

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Resum

© 2016 Elsevier Inc. Human parainfluenza virus type 3 (HPIV-3) is one of the most common respiratory viruses particularly among young children and immunocompromised patients. The seasonality, prevalence and genetic diversity of HPIV-3 at a Spanish tertiary-hospital from 2013 to 2015 are reported. HPIV-3 infection was laboratory-confirmed in 102 patients (76%, under 5 years of age). Among <5 years-old patients, 9 (11.5%) were under any degree of immunosuppression, whereas this percentage was significantly higher (19; 79.2%) among patients older than 5 years. HPIV-3 was detected at varying levels, but mainly during spring and summer. All characterized HN/F sequences fell within C1b, C5 and in other two closely C3a-related groups. Furthermore, a new genetic lineage (C1c) was described. Genetic similarity and epidemiological data confirmed some nosocomial infections, highlighting the importance of the HPIV-3 surveillance, particularly in high-risk patients. This study provides valuable information on HPIV-3 diversity due to the scarce information in Europe.
Idioma originalAnglès
Pàgines (de-a)153-159
RevistaDiagnostic Microbiology and Infectious Disease
Volum86
Número2
DOIs
Estat de la publicacióPublicada - 1 d’oct. 2016

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