TY - JOUR
T1 - A case of transitional cell carcinoma of the bladder with a del(9)(q11q21.2)
AU - Bernués, Marta
AU - Casadevall, Carme
AU - Miró, Rosa
AU - Caballín, M. Rosa
AU - Gelabert, Antoni
AU - Egozcue, Josep
PY - 1993/1/1
Y1 - 1993/1/1
N2 - Monosomy for chromosome 9, as well as loss of heterozygosity for markers on this chromosome, has been detected in a high percentage of transitional cell carcinomas (TCC) of the bladder. We report a case of a TCC of the bladder with an interstitial del(9)(q11q21.2) that could be indicative of the presence of a putative tumor-suppressor gene related to bladder tumor progression. To elucidate the role of chromosome 9 in bladder tumors, it would be interesting to study a possible loss of heterozygosity in this chromosome region. © 1993.
AB - Monosomy for chromosome 9, as well as loss of heterozygosity for markers on this chromosome, has been detected in a high percentage of transitional cell carcinomas (TCC) of the bladder. We report a case of a TCC of the bladder with an interstitial del(9)(q11q21.2) that could be indicative of the presence of a putative tumor-suppressor gene related to bladder tumor progression. To elucidate the role of chromosome 9 in bladder tumors, it would be interesting to study a possible loss of heterozygosity in this chromosome region. © 1993.
U2 - 10.1016/0165-4608(93)90120-B
DO - 10.1016/0165-4608(93)90120-B
M3 - Article
SN - 0165-4608
VL - 69
SP - 76
EP - 77
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
ER -