Detalls del projecte
Description
The new insights in telomere maintenance and telomerase activity as keypoints in tumour. The increased knowledge in induction and repair of DNA damage have raised large concern in the link between two process. TELORAD aims to determine the mechanistic link between telomerase, telomere binding protein and DNA repair gene and their respective role in the radiosensitivity. Mechanisms of stabilisation of the broken end, start point to the transmission of the radiation induced damage will be studied. Long term consequences as gene amplification and chromosome imbalance will be researched to identify the involvement of telomere maintenance in Hypersensitivity of individuals.
| Estatus | Acabat |
|---|---|
| Data efectiva d'inici i finalització | 1/02/00 → 31/01/03 |
Socis col·laboradors
- Universitat Autònoma de Barcelona (UAB)
- Consell Superior d'Investigacions Científiques (CSIC) (Associat)
- Commissariat à l'énergie atomique et aux énergies alternatives (Coordinador) (guia)
- Università degli Studi di Pavia (UNIPV) (Associat)
- Brunel University London (Associat)
- Consiglio Nazionale delle Richerche (Associat)
- Fundación Centro Oncológico de Galicia "José Antonio Quiroga y Piñeyro" (Associat)
Finançament
- Comissió Europea (CE): 540.479,00 €
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