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MECHANISMS OF NEURODEGENERATION AND NOVEL THERAPEUTIC TARGETS IN TAUOPATHIES
Solé, Montse
(PI)
Badillos, Raquel
(Col.laborador/a)
Morkoç, Kader
(Col.laborador/a)
Zhang, Jilun
(Col.laborador/a)
Institut de Neurociències (INc)
Kastamoni
Universitat Autònoma de Barcelona (UAB)
Informació general
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Keyphrases
Aged Mice
5%
AIMS™
5%
Alzheimer's Disease
17%
Alzheimer's Disease Model
5%
Alzheimer's Disease Patient
5%
Anti-apoptotic Proteins
5%
Apoptosis
100%
Apoptotic Caspases
5%
Behavioral Tests
5%
Biochemical Parameters
5%
Caspase
5%
Caspase-3
11%
Cell Death
5%
Clinical Severity
5%
Dementia
5%
Dendritic Pruning
5%
Disease Spectrum
5%
Hippocampus
5%
Human Brain Tissue
5%
Immortalized Cell
5%
In Vitro Approach
5%
Inhibitory Molecules
100%
Intracellular Neurofibrillary Tangles
5%
Loss Function
5%
Memory Test
5%
Neurodegeneration
100%
Neuronal Apoptosis
5%
Neuronal Death
17%
Neuronal Primary Cultures
5%
Neuropathology
5%
New Drug Targets
5%
Novel Therapeutic Targets
100%
Overexpression
5%
P301S
5%
Pathologic
5%
Pathological Conditions
5%
Pathological Progression
11%
Phosphorylation
5%
Physiologic
5%
Physiological Condition
5%
Physiopathological Mechanisms
5%
Regulatory Process
5%
Synaptic Activity
5%
Synaptic Plasticity
5%
Tau Function
11%
Tau Modification
5%
Tau Pathology
17%
Tau Post-translational Modification
5%
Tau Protein
5%
Tauopathy
100%
Tauopathy Mouse Model
5%
Therapeutic Effect
5%
Ubiquitination
23%
Xiap
5%
β-amyloid Peptide
5%
Neuroscience
Alzheimer's Disease
100%
Amyloid Beta Protein
20%
Caspase
20%
Caspase 3
40%
Cell Death
20%
Fas Receptor
20%
Hippocampus
20%
Immortalised Cell Line
20%
In Vitro
40%
Memory Test
20%
Neuroapoptosis
20%
Neurodegeneration
100%
Neuronal Cell Death
60%
Posttranslational Modification
20%
Primary Culture
20%
Synaptic Plasticity
20%
Tau Protein
20%
Tauopathy
100%
Ubiquitination
80%
XIAP
20%
Biochemistry, Genetics and Molecular Biology
Amyloid Beta
9%
Caspase
9%
Caspase 3
18%
Cell Death
9%
Dynamics
9%
Fas Receptor
9%
Mouse Model
18%
Nerve Cell Plasticity
9%
Neuroapoptosis
9%
Neurofibrillary Tangle
9%
Posttranslational Modification
9%
Primary Culture
9%
Tau
100%
Tau Protein
9%
Ubiquitination
36%
XIAP
9%