Implications of Medical Low Dose Radiation Exposure (MEDIRAD)

Detalls del projecte


MEDIRAD aims to enhance the scientific bases and clinical practice of radiation protection (RP) in the medical field and thereby addresses the need to understand and evaluate the health effects of low dose ionising radiation exposure from diagnostic and therapeutic imaging and from off-target effects in radiotherapy (RT).
MEDIRAD will pursue 3 major operational objectives: First, it will improve organ dose estimation and registration to inform clinical practice, optimise doses, set recommendations and provide adequate dosimetry for clinical-epidemiological studies of effects of medical radiation. Second, it aims to evaluate and understand the effects of medical exposures, focusing on the two major endpoints of public health relevance: cardiovascular effects of low to moderate doses of radiation from RT in breast cancer treatment incl. understanding of mechanisms; and long-term effects on cancer risk of low doses from CT in children. Third, it will develop science-based consensus policy recommendations for the effective protection of patients, workers and the general public.
Within the 4-year project a multi-disciplinary consortium will, in close interaction with European medical associations, MELODI and EURADOS (1), develop a tool to determine image quality to maximise optimisation of RP in medical imaging, (2) improve and develop new individual organ/anatomical structure dosimetry from chest CT, I131 administration, fluoroscopy-guided procedures, hybrid imaging, and RT for breast cancer and interlinks with image quality measures, (3) conduct epidemiological studies of consequences of RT and CT, (4) identify potential novel imaging and circulating biomarkers and mechanisms of radiation effects, (5) develop innovative risk models, (6) develop and implement for the first time a European repository of patient dose and imaging data, (7) develop science-based recommendations, and (8) introduce novel approaches to bring together the nuclear and medical sectors.
Data efectiva d'inici i finalització1/06/1728/02/22

Socis col·laboradors

  • EIBIR gemeinnützige GmbH zur Förderung der Erforschung der biomedizinischen Bildgebung (Coordinador) (guia)
  • University College Dublin (UCD) (Soci projecte)
  • Université Paris V René Descartes (Soci projecte)
  • University of Bristol (Soci projecte)
  • Associação para Investigação e Desenvolvimento da Faculdade de Medicina (CCUL) (Soci projecte)
  • B-Com (Soci projecte)
  • Otto-von-Guericke Universitat Magdeburg (Soci projecte)
  • Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (Soci projecte)
  • Institut Català d'Oncologia (ICO) (Soci projecte)
  • Instytut Medycyny Pracy Im. Prof. J.Nofera ( Nofer Institute of Occupational Medicin) (Soci projecte)
  • Institut National de la Santé et de la Recherche Médicale (INSERM) (Soci projecte)
  • Institut de Radioprotection et de Sûrete Nucléaire (IRSN) (Soci projecte)
  • Institut de Salut Global de Barcelona (ISGlobal) (Soci projecte)
  • Istituto Superiore di Sanità (ISS) (Soci projecte)
  • Klinikum Rechts der Isar der Technischen Universitaet Muenchen (Soci projecte)
  • University of Newcastle-upon-Tyne (Soci projecte)
  • Philipps Marburg Universität (Soci projecte)
  • The Royal Marsden NHS Foundation Trust (Soci projecte)
  • Centre d'Etude de l'Energie Nucléaire SCK·CEN (Soci projecte)
  • Universidade de Coimbra (UC) (Soci projecte)
  • Ghent University (Universiteit Gent) (Soci projecte)
  • Universitaetsklinikum wuerzburg - klinikum der bayerischen julius-maximilians-universität (Soci projecte)
  • Academisch ziekenhuis groningen (Soci projecte)
  • Stichting Vu-Vumc (Soci projecte)
  • Panepistimio Kritis (University of Crete) (Soci projecte)
  • Johannes Gutenberg University of Mainz (Soci projecte)
  • Università degli Studi di Roma-Sapienza (Soci projecte)
  • Universitat Politècnica de Catalunya (UPC) (Soci projecte)
  • Vastra Gotalands Lans Landsting (VGR) (Soci projecte)


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