Desarrollo de estrategias y agentes terapéuticos innovadores

Keyphrases

1. In Vitro Study 100%
2. Inhibitor Synthesis 100%
3. Amyloidogenesis Inhibitors 100%
4. Inhibitor Design 100%
5. Photoactivatable 100%
6. Transthyretin 100%
7. Pt(II) Complexes 100%
8. Inhibitor Evaluation 100%
9. Semisquaraines 100%
10. Cancer Cell Lines 66%
11. Photoactivation 66%
12. Cisplatin Resistance 66%
13. A2780 33%
14. Combined Mode 33%
15. Cytotoxic Effect 33%
16. New Ligand 33%
17. X-ray Diffraction (XRD) Analysis 33%
18. New Complexes 33%
19. Structural Modification 33%
20. Biological Media 33%
21. Trans Configuration 33%
22. Mode of Action 33%
23. A2780 Cells 33%
24. Photodegradation Process 33%
25. Cytotoxic Activity 33%
26. Cell Culture 33%
27. Density Functional Calculations 33%
28. Irradiation 33%
29. HeLa Cells 33%
30. Mechanism of Action 33%
31. Structural Identification 33%
32. Full Characterization 33%
33. Biological Evaluation 33%
34. Photoproducts 33%
35. Platinum Complexes 33%
36. Photoactive 33%
37. Resistant Cancer Cells 33%
38. Photochemical Properties 33%
39. Molecular Dynamics Simulation 28%
40. Small Molecules 14%
41. Rational Design 14%
42. Halogenated 14%
43. Binder 14%
44. Potent Drugs 14%
45. Amyloid Deposition 14%
46. Molecular Dynamics 14%
47. Fatal Infection 14%
48. Tolcapone 14%
49. Transthyretin Amyloidosis 14%
50. Kinetic Stabilizer 14%
51. Misfolding 14%
52. Tetramer Stability 14%
53. Dissociation 14%
54. Assisted Design 14%
55. High Affinity 14%
56. Protein-ligand 14%
57. Therapeutic Strategies 14%
58. Clinical Trials 14%