Replication data for "Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor-uptake of a tumor-targeted protein"

The dataset includes the physicochemical and in vivo characterization data supporting the article “Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor-uptake of a tumor-targeted protein.” It contains measurements of protein size, polydispersity, zeta potential, morphology, and release kinetics of zinc-induced secretory granules (SGs) obtained by DLS, FESEM, and TEM, as well as fluorescence-based biodistribution data in mice after subcutaneous, intramuscular, and intraperitoneal administration. The results demonstrate that subcutaneous administration ensures the most sustained protein release and highest tumor accumulation of the CXCR4-targeted T22-GFP-H6 protein.